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Synthesis of Azetidines from Imines by Cycloaddition Reactions presents several methodologies for the synthesis of azetidines from imines by cycloaddition reactions. The azetidines, known as important contribution of science to humanity, are important organic compounds that have occupied a basic position in the pharmaceutical chemistry for over a hundred years because of their biological activities. They are the fundamental skeleton of several antibiotics, probiotics and alkaloids. The synthesis of azetidines is a constant challenge for medicinal chemists, hence this book comprehensively describes azetidine ring synthesis.
With this book, readers will be able to quickly assess possible synthetic approaches and evaluate whether preparation of a four-membered nitrogen containing ring is reasonable.
List of contents
1. Synthesis of azetidines from imines 2. Synthesis of azetidines by cycloaddition of imines to alkenes 3. Synthesis of azetidines by metal-catalyzed cycloaddition of imines to alkenes 4. Synthesis of azetidines by cycloaddition of imines to ketenes-I 5. Synthesis of azetidines by cycloaddition of imines to ketenes-II 6. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds 7. Synthesis of azetidines by cycloaddition of imines to acetyl chloride moiety 8. Synthesis of azetidines by cycloaddition of imines to aromatic acetyl chloride moiety 9. Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-I 10. Synthesis of azetidines by cycloaddition of imines to chloroacetyl chloride-II
About the author
Dr. Navjeet Kaur received her BSc from Panjab University Chandigarh (Panjab, India) in 2008. In 2010, she completed her MSc in Chemistry from Banasthali Vidyapith. She was awarded with PhD in 2014 by the same university. With 11 years of teaching experience, she has published over 160 scientific research papers, review articles, book chapters, and monographs in the field of organic synthesis in national and international reputed journals. She has published five authored books: with Elsevier. She secured her place amongst top 2% scientists of the world in 2017 (single year ranking), 2018 (full career wise ranking), 2019 [full career wise ranking with 424 world rank (04 in India) and single year ranking with 03 world rank (01 in India)] and 2020 (full career wise ranking with 372 world rank and single year ranking with 126 world rank). In 2021, Dr. Kaur was chosen as a candidate for membership by Royal Society of Research, London, England, UK with full waiver of application fees. She is serving as an Editor-in-Chief of the “Advanced Chemicobiology Research” journal.
