Dermatological and Transdermal Formulations

Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts discuss the bioequivalence of dermatological and transdermal dosage forms. They explore the biochemistry and treatment of skin diseases, the structure and function of the skin, adverse dermal responses to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation.

List of contents

The structure and function of the skin; common skin disorders and their topical treatment; basic mathematical principles in skin permeation; skin transport; methods for studying percutaneous absorption; formulation strategies for modulating skinpermeation; formulation and development of dermatological dosage forms; bioequivalence of dermal and transdermal formulations; scale-up of dermatological dosage forms; a case for multivariate optimization and product homogeneity; transdermal drug deliverysystems; safety considerations for dermal and transdermal products; transdermal delivery and cutaneous reactions.

About the author

Kenneth A. Walters

Summary

Provides an coverage of the development, preparation, and application of topical and transdermal therapeutic systems. This book discusses the bioequivalence of dermatological and transdermal dosage forms. It explores the biochemistry and treatment of skin diseases, the structure and function of the skin, and more.

Product details

• Assisted by: Kenneth A. Walters (Editor), Walters Kenneth A. (Editor)
• Publisher: Taylor and Francis
• Languages: English
• Product format: Hardback
• Released: 20.02.2002
• EAN: 9780824798895
• ISBN: 978-0-8247-9889-5
• No. of pages: 592
• Weight: 1260 g
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; Social sciences, law, business > Business > Individual industrial sectors, branches; Medicine: general issues, MEDICAL / Dermatology, SCIENCE / Chemistry / General, MEDICAL / Pharmacology, environmental science, engineering & technology, Dermatology, Biology, life sciences, Engineering: general, Pharmaceutical technology, Manufacturing industries, Environmental science, engineering and technology, Pharmaceutical industries, Pharmaceutical chemistry and technology