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Informationen zum Autor Desmond J. Brown is Professor of Chemistry at The Australian National University. Klappentext This volume in the Chemistry of Heterocyclic Compounds series presents a comprehensive review of the quinoxaline literature from 1975 to the present (2002)! updating Volumes 5 and 35. It provides an alphabetical table of known simple quinoxalines! including new compounds discussed in this volume and their physical data! as well as the pyrazines from the original volumes. Biological activities! spectral or other physical studies! and other such materials appear at appropriate points in the text. The in-depth coverage includes synthesis! reactions! spectroscopic! and physical properties for each class of compounds. Chemistry of Heterocyclic Compounds! Volume 61: Supplement II provides the most up-to-date summation of knowledge of the synthetic chemistry of quinoxalines. Zusammenfassung Reviews various quinoxaline literature from 1975 onwards! designed for use in conjuction with earlier reviews. Inhaltsverzeichnis Chapter 1 Primary Syntheses 1 1.1 From a Single Benzene Substrate 1 1.1.1 By Formation of the N1,C8a Bond 1 1.1.2 By Formation of the N1,C2 Bond 4 1.1.2.1 Cyclization of o -(Ethylamino)aniline Derivatives 4 1.1.2.2 Direct Cyclization of o -(Ethylamino)nitrobenzene Derivatives 6 1.1.2.3 Reductive Cyclization of o -(Ethylamino)nitrobenzene Derivatives 8 1.1.3 By Formation of the C2,C3 Bond 12 1.2 From a Benzene Substrate with an Ancillary Synthon 13 1.2.1 When the Synthon Supplies N1 of the Quinoxaline 13 1.2.2 When the Synthon Supplies C2 of the Quinoxaline 14 1.2.3 When the Synthon Supplies C2 + C3 of the Quinoxaline 16 1.2.3.1 Using a Dialdehyde (Glyoxal) or Related Synthon 16 1.2.3.2 Using an Aldehydo Ketone or Related Synthon 18 1.2.3.3 Using an Aldehydo Acid or Related Synthon 22 1.2.3.4 Using an Aldehydo Ester or Related Synthon 23 1.2.3.5 Using an Aldehydo Amide, Nitrile, Acyl Halide, or Related Synthon 24 1.2.3.6 Using a Diketone or Related Synthon 24 1.2.3.7 Using a Keto Acid or Related Synthon 30 1.2.3.8 Using a Keto Ester or Related Synthon 31 1.2.3.9 Using a Keto Amide, Nitrile, Acyl Halide, or Related Synthon 34 1.2.3.10 Using a Diacid (Oxalic Acid) as Synthon 35 1.2.3.11 Using a Diester (a Dialkyl Oxalate) or Related Synthon 36 1.2.3.12 Using an Estero Amide, Nitrile, Acyl Halide, or Related Synthon 38 1.2.3.13 Using a Diamide (Oxamide), Amido Nitrile, or Related Synthon 40 1.2.3.14 Using a Diacyl Dihalide (Oxalyl Halide) or Related Synthon 40 1.2.4 When the Synthon Supplies N1 + C2 + C3 of the Quinoxaline 42 1.2.5 When the Synthon Supplies N1 + C2 + C3 + N4 of the Quinoxaline 42 1.3 From a Benzene Substrate with Two or More Synthons 44 1.4 From a Pyrazine Substrate with or without Synthon(s) 45 1.5 From Other Heteromonocyclic Substrates/Synthons 46 1.5.1 Azirines as Substrates/Synthons 47 1.5.2 1,2,3-Dithiazol-1-iums as Substrates/Synthons 47 1.5.3 Furans as Substrates/Synthons 48 1.5.4 Isothiazoles as Substrates/Synthons 49 1.5.5 Isoxazoles as Substrates/Synthons 50 1.5.6 Oxazoles as Substrates/Synthons 51 1.5.7 Oxirenes as Substrates/Synthons 51 1.5.8 Pyrans as Substrates/Synthons 53 1.5.9 Pyridazines as Substrates/Synthons 53 1.5.10 Pyridines as Substrates/Synthons 54 1.5.11 Pyrimidines as Substrates/Synthons 54 1.5.12 Pyrroles as Substrates/Synthons 55 1.5.13 Thiophenes as Substrates/Synthons 55 1.5.14 1,2,4-Triazines as Substrates/Synthons 56 1.5.15 1,2,3-Triazoles as Substrates/Synthons 56 1.6 From Heterobicyclic Substrates/Synthons 57 1.6.1 7-Azabicyclo[4.1....
