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Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery.
As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study.
List of contents
1. Introduction
2. Fabrication of Microneedles
3. Dissolving Microneedles
4. Anatomy and Physiology of the Eye
5. Microneedle-Assisted Drug Delivery to the Eye
6. Microneedles for Diagnostic Testing
7. Therapeutic Drug Monitoring with Microneedles
8. Miscellaneous Routes of Microneedle-Assisted Drug Delivery
9. Mathematical Modeling of Drug Delivery from Microneedles
10. Solid Microneedles
11. Coated Microneedles
12. Hollow Microneedles
13. Hydrogel-forming Microneedles
About the author
Dr. Ita holds a PhD in Pharmaceutics. His area of expertise is transdermal drug delivery. He has over 40 publications in this area and teaches Pharmaceutics to both first- and second year pharmacy students at the College of Pharmacy, Touro University, California. He joined the University in 2006 as an Assistant Professor and is now a Full Professor. He was awarded an ICRETT Fellowship by the International Union Against Cancer (IUCC).
Report
"This book discusses various aspects of microneedle technology, a novel drug delivery system,... [and] provides an overview of the development of microneedle-based drug delivery systems.... [R]eaders are expected to find it a handy reference.... In 13 chapters, the author presents the recent advancements in microneedle-based devices by discussing the selection of materials, fabrication techniques, sterilization methods, classification, and pharmaceutical application of microneedles.... This book provides basic microneedles principles and advances and briefly introduces the general fabrication strategies, which the audience will find as a handy reference...." --Rahmat M. Talukder, PhD, RPh(The University of Texas at Tyler)