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Informationen zum Autor I am currently Professor of Chemistry and Biological Chemistry at the University of Michigan in Ann Arbor. My research interests center on enzyme mechanisms and protein structure and design. We are currently working on a variety of research projects. In particular, we have a long-standing interest in enzymes that use free radicals to catalyze a variety of unusual chemical transformations. More recently, we have become interested in enzymes involved in hydrocarbon biosynthesis, many of which have novel mechanisms and are of practical interest for the biosynthesis of next-generation biofuels. We are also interested in understanding in molecular detail how enzymes interact with abiological surfaces as this is key to many industrial and biomedical applications where enzymes are immobilized on solid supports. More information about my research can be found here:http://www.lsa.umich.edu/chem/people/faculty/ci.marsheneilg_ci.detail
List of contents
1. B12 Biosynthesis and B12 Chaperones
Martin Warren University of Kent, U.K.
2. Biosynthesis of corrinoids
Amrita Hazra IISER Pune, India
3. Guardian of cobamide diversity: probing the role of CobT in lower ligand activation in the biosynthesis of vitamin B12 and other cobamide cofactors
Michiko Taga University of California, Berkeley
4. Purification and Detection of Vitamin B12 Analogs
Jorge Escalante-Semerena University of Georgia
5. A method for the efficient adenosylation of corrinoids
Jorge Escalante-Semerena University of Georgia
6. A method for the production, purification and liposome reconstitution of cobamide synthase
Jorge Escalante-Semerena University of Georgia
7. A method for the Isolation of -ribazole from Vitamin B12, and its Enzymatic Conversion to -ribazole 5'-phosphate
Ruma Banerjee University of Michigan
8. The human B12 trafficking chaperones: CblC, CblD and ATR
Bernhard Kräutler University of Innsbruck, Austria
9. Synthesis and applications of "antivitamin" B12 derivatives B12-dependent enzyme reactions
Tetsuo Toraya Okayama University, Japan
10. Coenzyme B12-dependent eliminases: Diol and glycerol dehydratases and ethanolamine ammonia-lyase
Tetsuo Toraya Okayama University, Japan
11. Reactivating chaperones for coenzyme B12-dependent eliminases: Diol and glycerol dehydratases and ethanolamine ammonia-lyase
Wolfgang Buckel Marburg University
12. Glutamate mutase and 2-methyleneglutarate mutase
Ruma Banerjee University of Michigan
13. Human B12 dependent enzymes: Methionine synthase and methylmalonyl-CoA mutase
David Leys Manchester University
14. Heterologous production and biophysical characterisation of catabolic Nitratireductor pacificus pht-3B reductive dehalogenase
Nigel Scrutton Manchester University
15. An unusual light-sensing function for coenzyme B12 in bacterial transcription regulator CarH
