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Asthma in the 21st Century: New Research Advances provides an overview on asthma, with discussions on its heterogeneity, risk factors and their interrelations, and e-health in an aging world based on current research knowledge. The book covers heterogeneity of the disease beyond severe asthma, new risk factors, new diagnoses with climate change, a focus on chemical exposures at home, e-health and links with aging, and notable advances in key areas such as diet and microbiota, the genetics of asthma, and the asthma versus COPD debate. Worldwide, the total number of asthma sufferers is estimated to be ~270 million with an additional 100 million expected to develop asthma by 2025, and asthma is the most common chronic disease among children. There are a number of clinical books available on asthma, but none with much discussion on current scientific findings and new disease understanding. Yet, the concept of asthma has evolved quickly in the past 5-10 years, with many clinicians struggling to keep up with new scientific findings.
List of contents
1. Asthma: From one disease to endotypes
2. Eosinophilic and noneosinophilic asthma: Beyond severe asthma
3. Airway microbiome and asthma
4. Gender differences and sex-related hormonal factors in asthma
5. Diet and asthma
6. Indoor air and respiratory health: Volatile organic compounds and cleaning products
7. Outdoor air pollution and asthma in a changing climate
8. Genetic and epigenetic links to asthma risk
9. Asthma and COPD: distinct diseases or components of a continuum?
10. Asthma in an aging world
11. Asthma in the digital world
About the author
Dr Rachel Nadif is a Senior Researcher at French Institute of Health and Medical Research (inserm) and the Head of the Integrative Respiratory Team in the Centre for Epidemiology and Population Health (Inserm U1018). She has a background in biology and epidemiology, and a strong expertise in respiratory epidemiology. Her research program aims to refine asthma phenotypes by including biological markers, and to better understand the etiology of asthma and rhinitis by studying the associations with environment, genes and their interactions.