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Tinnitus and Hyperacusis: Facts, Theories, and Clinical Implications provides an overview on this burgeoning field, covering the underlying mechanisms and potential treatments for these disorders. The book begins with an overview of the etiology and genetics behind tinnitus and hyperacusis. The author then proposes two parallel neural pathways underlying these conditions and provides a basis for connecting animal to human research. Neurotransmitters, neuromodulators and immediate early genes are discussed, along with a detailed comparison of about a dozen models aimed at explaining tinnitus and hyperacusis, including the neurophysiological model, the neural synchrony model and the cortical map reorganization and filling-in model.
Potential treatments of tinnitus and hyperacusis, from behavioral to non-invasive neuromodulation are also discussed. This book is written for clinical neuroscientists, audiologists, neuro-otologists, neurologists and clinical psychologists.
List of contents
1. Tinnitus, hyperacusis, and hearing loss
2. Epidemiology, etiology, and genetics
3. Physiological markers of tinnitus and hyperacusis
4. Substrates of tinnitus and hyperacusis in the animal auditory system
5. Evoked potentials and neuroimaging in humans with tinnitus
6. Tinnitus and hyperacusis: The nonclassical auditory system
7. Tinnitus and the nonauditory brain
8. Loudness recruitment and hyperacusis: The central-gain model
9. Bottom-up tinnitus models
10. Top-down tinnitus models
11. Behavioral and pharmaceutical therapy
12. Neurofeedback and neuromodulation: Hearing aids, cochlear implants, and transcranial stimulation
About the author
Dr. Jos J. Eggermont is an Emeritus Professor in the Departments of Physiology and Pharmacology, and Psychology at the University of Calgary in Alberta, Canada. Dr. Eggermont is one of the most renowned scientists in the field of the auditory system and his work has contributed substantially to the current knowledge about hearing loss. His research comprises most aspects of audition with an emphasis on the electrophysiology of the auditory system in experimental animals. He has published over 225 scientific articles, authored/edited 10 books, and contributed to over 100 book chapters all focusing on the auditory system.
