Read more
This useful guide for designing effective transformations by using homologation reactions is a must-read for every synthetic chemist in academia and industry.
List of contents
Foreword
Preface
Acknowledgments
VOLUME I
1 Diazo-Mediated Homologation Reactions
2 Lithium Carbenoids in Homologation Chemistry
3 Streamlining C1 Homologation Reactions Using Continuous Flow Technology: Focus on Diazomethane and Methyllithium Chemistry
4 Magnesium Carbenoids in Homologation Chemistry
5 Homologation Reactions Based on Zinc Carbenoids and Related Reagents
6 Homologations via Carbene-Mediated Rearrangement Reactions
7 Oxenoids as Homologation Partners
8 Sulfur Ylides as C1 Homologating Reagents
9 Modern Homologation Reactions of Sulfoxonium Ylides via C-H Activation
10 Phosphorus Reagents for Two-, Three-, and Four-Carbon Homologation of Carbonyl Compounds to Functionalized Olefins
11 Homologation Tactics with Diborylmethane via alpha-Boryl Carbanions
VOLUME II
12 Homologation of Boronic Acids and Organoboranes by Transition-Metal-Free Reactions with Diazo Compounds and N-Sulfonylhydrazones
13 Stereospecific Reagent-Controlled Homologation Using Carbenoids Generated by Sulfoxide-Metal Exchange
14 Iterative Homologation of Boronic Esters: Assembly Line Synthesis
15 Fluorocarbon Chain Homologation and Elongation Reactions
16 Homologation Reactions for the Synthesis of Fluorinated Molecules
17 Synthesis of Oxiranes and Aziridines from Aldehydes and Imines Using Anionic Homologation Approaches
18 One-Carbon Homologation and Homologation-Functionalization Reactions of Aldehydes
19 Ring Expansion Homologation: Synthetic Strategies and Reaction Design
20 Dehomologations and Ring Contraction Strategies
21 Direct Radical C1 Homologations
22 Allenation of Terminal Alkynes for Allene Synthesis
23 Homogeneous Carbon Monoxide Homologation
24 Homologation Reactions with Carbon Dioxide
Index
About the author
Vittorio Pace is full professor of organic chemistry at the University of Torino, Italy, since 2020. From 2018 to 2020, he was a tenure-track professor in drug synthesis at the University of Vienna, Austria. He received several awards including the La Roche-Hoffmann Prize of the European Society of Medicinal Chemistry, and the Habilitation Award of the Austrian Chemical Society in 2019. His research is focused on the design and development of new synthetic concepts with functionalized organometallic reagents.
Summary
This useful guide for designing effective transformations by using homologation reactions is a must-read for every synthetic chemist in academia and industry.
