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Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.
List of contents
1. CANCER BURDEN: EPIDEMIOLOGY, RACIAL AND GEOGRAPHICAL DISPARITIES
Shaveta Menon and Ramila Bisht2. MILESTONES IN CANCER RESEARCH
Siddharth Sharma3. TECHNOLOGICAL EVOLUTION IN CANCER DIAGNOSISAND THERAPEUTICS
Sudeep Bose I4. HOW DOES TIME SPEAK ABOUT CANCER, ITS DIAGNOSIS, TREATMENTS AND CHALLENGES?
Asit Ranjan Ghosh5. ROLE OF ARTIFICIAL INTELLIGENCE IN CANCER DIAGNOSTICS AND THERAPEUTICS
B. Medhi6. ADDRESSING THE DIAGNOSIS AND THERAPEUTICS OF MALIGNANT TUMOUR CELLS
Anjoy Mahji7. SOMATIC MUTATION: PHARMACOGENOMICS IN ONCOLOGY CARE
Shamsher Singh8. INSIGHTS INTO GENETIC PREDISPOSITION OF SOMATIC CANCERS
B. Medhi9. THE USE OF TUMOR MARKERS IN PROGNOSIS OF CANCER AND STRATEGIES TO PREVENT CANCER PREDISPOSITION AND PROGRESS
Osama Ahmed, Mohamed Abd-Elbaset, Noha Ahmed and Eman Abd Elhaliem10. CYTOGENETICS TO MULTI-OMICS IN BIOLOGY OF CANCER
Sikander S. Gill11. ROLE OF NON-CODING RNA AS BIOMARKERS FOR CANCER
Bikash Medhi and B. Medhi12. VIRAL miRNA's: DIAGNOSTIC AND PROGNOSTIC BIOMARKERS FOR CANCER AND INFECTIOUS DISEASE
Sunil Babu Gosipatala, Dr. Abhishek Pandeya, Raj Kumar Khalko, Ranbir C. Sobti Sr., Sneha Kumari, Prashansa Khanna and Utkarsha Vishwakarma13. PHARMACOGENOMICS AND ONCOLOGY: A THERAPEUTIC APPROACH FOR CANCER TREATMENT
Shamsher Singh and Anil Kumar14. ENVIRONMENTAL FACTORS INFLUENCING EPIGENETIC CHANGES INITIATING NEOPLASTIC CHANGES
B. Medhi15. OBESITY: EMERGING RISK FACTOR FOR CANCER BEYOND METABOLIC SYNDROME
Ranbir C. Sobti Sr.16. HOMOLOGOUS REPAIR DEFICIENCY AND PARP INHIBITORS IN CANCER MANAGEMENT
Shivani Arora Mittal17. MOLECULAR PROSPECTS OF TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES (TALENS) IN CANCER
Mani Chopra18. IMMUNO PEPTIDOMIC APPROACHES FORMANAGEMENT OFCANCER
B. Medhi19. REGULATION OF TUMOR MICROENVIRONMENT BY NUTRIENT TRAFFICKING
B. Medhi20. PRECISION MEDICINE : DOSE FOR ANTI CANCER THERAPY
Dr Shiva Tushir
About the author
Dr. Ranbir Chander (RC) Sobti is Emeritus Professor at Punjab University, Chandigarh, and Honorary Scientist at the Indian National Science Academy. He started his career as a cytogeneticist and progressed to molecular biology and disease processes of cancer, COPD, AIDS, metabolic syndrome, and kidney diseases. He is a Fellow of the Third World Academy of Sciences, National Academy of Sciences India, Indian National Science Academy, National Academy of Medical Sciences, National Academy of Agricultural Sciences, Canadian Academy of Cardiovascular Diseases Royal Society of biology and international Association of Cancer Research. Dr. Sobti has participated in several book projects, including Elsevier’s Advances in Animal Experimentation and Modeling; Biomarkers in Cancer Detection and Monitoring of Therapeutics; Molecular Medicine and Biomedical Research in the Era of Precision Medicine; One Planet, One Health, One Future; Probiotics; and Public and Environmental Health.Dr. Awtar Krishan PhD is a world-renowned scientist. He obtained his PhD from Panjab University (1962) and the Univ. of Western Ontario, Canada (1963) in Cytogenetics and Anatomy. From 1965 to 1977, he was at the Sidney Farber Cancer Institute, Harvard Medical School as Head of the Tissue Ultrastructure and Experimental Pathology Labs. He has developed flow cytometric techniques for rapid analysis of DNA content by hypotonic propidium iodide, monitoring of drug retention and resistance, and more recently for monitoring hormone receptor expression in archival tumors. He is currently Director, Analytical Cytometry Laboratory, at University of Miami.Aastha Sobti is a Doctoral student at the Department of Immunotechnology at Lund University, Sweden. Her research areas interests include translational medicine, clinical dentistry, cancer immunology, biomarkers, diagnostics and medical oncology. Aastha Sobti has written two books with Elsevier: "Biomarkers in Cancer Detection and Monitoring of Therapeutics" (2023) and Molecular Medicine and Biomedical Research in the Era of Precision Medicine (2025).
