Read more
Molecular Bases of Anesthesia provides a clear overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence and focusing on the latest state-of-the-art techniques that relate to how anesthetic drugs cause unconsciousness.
With contributions by leading experts, this timely book includes chapters on how to evaluate theories of anesthesia in general and includes discussion of some of the techniques, such as genetics, that can be used to address problems. Also discussed are anesthetic actions at major brain targets with a special emphasis on ion channels and areas of controversy in the field.
This reference provides a broad survey of anesthetic actions, including hyperbaric pressure and anesthesia; volatile anesthetic interactions with proteins; and structure activity relationships of volatile anesthetics. Molecular Bases of Anesthesia stands alone as an in-depth, authoritative guide.
List of contents
Basic Pharmacology of Volatile Anesthetics. Experimental Approaches to the Study of Volatile Anesthetic-Protein Interactions. Pressure and Anesthesia. Genetics and Anesthetic Mechanisms. Structure-Activity Relationships of Inhaled Anesthetics. Volatile Anesthetic Effects on Calcium
Channels. Inhalation Anesthetic Effects on Neuronal Plasma Membrane CA2+ -ATPASE. Anesthetic Modifications of Neuronal Sodium and Potassium Channels. Volatile Anesthetic Effects at Excitatory Amino Acid Receptors. Effects of Volatile Anesthetics on GABAA Receptors: Electricophysical Studies. Neurochemical Actions of Anesthetics at the GABAA Receptors. Stereoselective Effects of Volatile Anesthetics. Effects of Volatile Anesthetics at Nicotinic Acetylcholine Receptors.
About the author
Eric Moody, Phil Skolnick
Summary
Offers an overview of the state of knowledge about anesthetic mechanisms at the molecular level of occurrence, focusing on the techniques that relate to how anesthetic drugs cause unconsciousness. This book provides a survey of anesthetic actions, including hyperbaric pressure and anesthesia and volatile anesthetic interactions with proteins.
