Read more
Written by world experts in the field of neuronal chemoreception, Methods in Chemosensory Research describes new molecular, electrophysiological, genetic, behavioral, psychophysical, and imaging techniques that have recently been adapted to investigate the basic neuronal mechanisms underlying chemoreception: taste, olfaction and chemical-induced irritation. This unique book includes a wide variety of new and innovative imaging methods, electrophysiological methods, methods to investigate development, and various aspects of behavioral testing.
Covering the entire spectrum of chemoreception, each section not only describes what information can be obtained by using each method, but also shows how to apply each method to obtain reliable results. The book presents a comprehensive view of how the brain uses information about chemical stimuli that interact with receptors in the nose and tongue. Methods in Chemosensory Research gives you the new tools to learn how chemicals affect activity from the genetic to the behavioral levels.
List of contents
BEHAVIORAL STUDIES. Psychophysical Measurement of Oral Chemesthesis. Behavioral Methods in Olfactory Research with Rodents. MOLECULAR AND CELL BIOLOGY OF TASTE AND OLFACTION. Recordings from Vertebrate Olfactory Receptor Neurons: From Isolated Cells to Intact Epithelial Preparations. Recordings from Olfactory Receptor Neurons in the Rat in Vivo. Voltage-Sensitive and Calcium-Sensitive Dye Imaging of Activity in the Olfactory Bulb; Presynaptic Inhibition, Maps of Receptor Cell Input and Oscillations. Gustatory System Development: New Experimental Approaches in Amphibian and Mammalian Embryos. Mammalian Taste Receptors. Researching Isolated Taste Receptor Cells: Deciphering Transduction Cascades with Patch-Clamp And Calcium: Imaging Techniques. Rapid Kinetic Measurements in Chemosensory Systems. Electrophysiological Recordings of Mammalian Taste. HIGER-ORDER STUDIES IN TASTE AND OLFACTION. Activation of Neurons in the Trigeminal Subnucleus Caudalis (Vc) By Irritant Chemical Stimulation: Extracellular Single-Unit Recording and c-fos Immunohistochemical Methods. Methodological Considerations for Electrophysiological Recording and Analysis of Taste-Responsive Neurons in the Brainstem of the Rate. Electrophysiological Analysis of Olfactory Coding in the CNS. Electrophysiological Studies of Gustation in Awake Rats. Recording from Single Neurons in the Primary Taste Cortex of the Alert Macaque. Olfactory Learning and the Neurophysiological Study of Rat Prefrontal Function. Olfactory Event-Related Potentials. Application of Functional MRI in Olfactory Studies. Functional Imaging of Olfactory Activation in the Human Brain.
About the author
Miguel A. L. Nicolelis, Sidney A. Simon
Summary
Describes molecular, electrophysiological, engineering, genetic, behavioral, psychophysical, and imaging techniques that have been adapted to investigate the basic neuronal mechanisms underlying chemoreception. This book investigates various aspects of taste and olfaction.
