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Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex MHC; elucidation of its gene structure and polymorphism, as well as the molecular basis of MHC restriction; the arrangement, expression, and regulation of immunoglobulins; definition of the structure of the T cell receptor and organization of its genes; and the characterization of soluble factors involved in cell/cell interactions and cloning of their genes are among the major accomplishments. Volumes I and II build on these developments in basic immunology to introduce animal models of various diseases, corresponding human studies, and the genetic analysis of autoimmune traits at the patient population level. The book will be a tremendous asset to immunologists, geneticists, and physicians in various areas of clinical subspecialties.
List of contents
Volume II:Immunoglobulin and T Cell Redeptor Genes in SLEImmunogenetics of Systemic Lupus ErythematosusThe Genetics of Systemic Lupus ErythematosusThe Immunogenetic Basis of Sjogren's SyndromeImmunogenetics of Scleroderma and Mixed Connective Tissue DiseaseImmunogenetics of Experimental Myasthenia Gravis: Contribution of IgVh Genes Encoding Anti-Dextran Antibodies to Immune Responsiveness Against the Acetylcholine ReceptorImmunogenetics of Type II Collagen-Induced Arthritis in MiceImmunogenetics of Rheumatoid Arthritis and Ankylosing SpondylitisThyroid Autoimmunity in Experimental ModelsAutoimmune Thyroid DiseaseImmunogenetics of Type I DiabetesAutoimmune Hepatitis and Other Diseases of the Liver: Immunogenetic AspectsImmunogenetics of Pernicious AnemiaImmunogenetic Aspects of Inflammatory Bowel DiseaseImmunogenetics of Multiple SclerosisImmuinogenetics of Autoimmune Renal DiseaseImmunogenetics of Autoimmune Cutaneous DiseaseImmunogenetics of Autoimmune Polyglandular SyndromeImmunogenetics of AIDSIndex
About the author
Nadir R. Farid
Summary
Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions
