Organic Chemistry, International Adaptation

Organic Chemistry, 4th Edition provides a comprehensive, yet accessible treatment of all the essential organic chemistry concepts covered in a two-semester course. Presented with a skills-based approach that bridges the gap between organic chemistry theory and real-world practice, the book places special emphasis on developing their problem-solving skills through applied exercises and activities. It incorporates Klein's acclaimed SkillBuilder program which contains a solved problem that demonstrates a skill and several practice problems of varying difficulty levels?including conceptual and cumulative problems that challenge students to apply the skill in a slightly different environment. An up-to-date collection of literature-based problems exposes students to the dynamic and evolving nature of organic chemistry and its active role in addressing global challenges. The text is also enriched with numerous hands-on activities and real-world examples that help students understand both the "why" and the "how" behind organic chemistry.

List of contents

1 A Review of General Chemistry: Electrons, Bonds, and Molecular Properties 1
 
1.1 Introduction to Organic Chemistry 2
 
1.2 The Structural Theory of Matter 3
 
1.3 Electrons, Bonds, and Lewis Structures 4
 
1.4 Identifying Formal Charges 7
 
1.5 Induction and Polar Covalent Bonds 8
 
1.6 Reading Bond- Line Structures 11
 
1.7 Atomic Orbitals 14
 
1.8 Valence Bond Theory 17
 
1.9 Molecular Orbital Theory 18
 
1.10 Hybridized Atomic Orbitals 20
 
1.11 Predicting Molecular Geometry: VSEPR Theory 26
 
1.12 Dipole Moments and Molecular Polarity 30
 
1.13 Intermolecular Forces and Physical Properties 33
 
WorldLinks Biomimicry and Gecko Feet 37
 
BioLinks Drug- Receptor Interactions 38
 
1.14 Solubility 39
 
BioLinks Propofol: The Importance of Drug Solubility 40
 
Review of Concepts and Vocabulary * SkillBuilder Review Practice Problems * Integrated Problems * Challenge Problems
 
2 Molecular Representations 49
 
2.1 Molecular Representations 50
 
2.2 Bond- Line Structures 52
 
2.3 Identifying Functional Groups 54
 
BioLinks Marine Natural Products 55
 
2.4 Carbon Atoms with Formal Charges 57
 
2.5 Identifying Lone Pairs 57
 
2.6 Three- Dimensional Bond- Line Structures 60
 
BioLinks The Opioids 61
 
2.7 Introduction to Resonance 62
 
2.8 Curved Arrows 64
 
2.9 Formal Charges in Resonance Structures 66
 
2.10 Drawing Resonance Structures via Pattern Recognition 68
 
2.11 Assessing the Relative Importance of Resonance Structures 73
 
2.12 The Resonance Hybrid 77
 
2.13 Delocalized and Localized Lone Pairs 79
 
Review of Concepts and Vocabulary * SkillBuilder Review Practice Problems * Integrated Problems * Challenge Problems
 
3 Acids and Bases 91
 
3.1 Introduction to Brønsted- Lowry Acids and Bases 92
 
3.2 Flow of Electron Density: Curved- Arrow Notation 92
 
BioLinks Antacids and Heartburn 94
 
3.3 Brønsted- Lowry Acidity: Quantitative Perspective 95
 
BioLinks Drug Distribution and pK a 101
 
3.4 Brønsted- Lowry Acidity: Qualitative Perspective 102
 
3.5 Brønsted- Lowry Acidity: Assessing the Relative Acidity of Cationic Acids 113
 
3.6 Position of Equilibrium and Choice of Reagents 118
 
3.7 Leveling Effect 121
 
3.8 Solvating Effects 122
 
3.9 Counterions 123
 
WorldLinks Baking Soda versus Baking Powder 123
 
3.10 Lewis Acids and Bases 124
 
Review of Concepts and Vocabulary * SkillBuilder Review Practice Problems * Integrated Problems * Challenge Problems
 
4 Alkanes and Cycloalkanes 137
 
4.1 Introduction to Alkanes 138
 
4.2 Nomenclature of Alkanes 138
 
WorldLinks Pheromones: Chemical Messengers 142
 
BioLinks Naming Drugs 150
 
4.3 Constitutional Isomers of Alkanes 151
 
4.4 Relative Stability of Isomeric Alkanes 152
 
4.5 Sources and Uses of Alkanes 153
 
WorldLinks An Introduction to Polymers 155
 
4.6 Drawing Newman Projections 155
 
4.7 Conformational Analysis of Ethane and Propane 157
 
4.8 Conformational Analysis of Butane 159
 
BioLinks Drugs and Their Conformations 163
 
4.9 Cycloalkanes 163
 
BioLinks Cyclopropane as an Inhalation Anesthetic 165
 
4.10 Conformations of Cyclohexane 166
 
4.11 Drawing Chair Conformations 167
 
4.12 Monosubstituted Cyclohexane 169
 
4.13 Disubstituted Cyclohexane 171
 
4.14 cis-trans Stereoisomerism 175
 
4.15 Po

Summary

Organic Chemistry, 4th Edition provides a comprehensive, yet accessible treatment of all the essential organic chemistry concepts covered in a two-semester course. Presented with a skills-based approach that bridges the gap between organic chemistry theory and real-world practice, the book places special emphasis on developing their problem-solving skills through applied exercises and activities. It incorporates Klein's acclaimed SkillBuilder program which contains a solved problem that demonstrates a skill and several practice problems of varying difficulty levels?including conceptual and cumulative problems that challenge students to apply the skill in a slightly different environment. An up-to-date collection of literature-based problems exposes students to the dynamic and evolving nature of organic chemistry and its active role in addressing global challenges. The text is also enriched with numerous hands-on activities and real-world examples that help students understand both the "why" and the "how" behind organic chemistry.

Product details

• Authors: Klein, David R Klein, David R. Klein, David R. (Johns Hopkins University) Klein, Dr Klein, Klein David R.
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Paperback / Softback
• Released: 05.04.2022
• EAN: 9781119820833
• ISBN: 978-1-119-82083-3
• No. of pages: 1392
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Organic chemistry; Chemie, Organische Chemie, ORGANIC CHEMISTRY, chemistry