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Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.
The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.
List of contents
Section 1: Introduction
1. General introduction, occurrence, physicochemical and spectroscopic data
2. Chemical reactivity
3. Ring Synthesis
Section 2: Medicinal Chemistry
4. Anti-infective agents
5. Anticancer agents
6. Alzheimer's disease therapy
7. Enzyme inhibitors
Section 3: Inorganic Chemistry and Materials Science
8. Pyridine metal complexes as heterogeneous catalysts in organic synthesis
9. Pyridine-based probes and chemosensors
10. Pyridine-based polymers
About the author
Dr. Parvesh Singh is a seasoned synthetic organic and medicinal chemist with a keen interest in heterocyclic scaffolds and their medicinal applications. He obtained his Ph.D. in 2006 from the Guru Nanak Dev University under the supervision of Professor Mohinder P Mahajan. He is currently an Associate Professor in the School of Chemistry and Physics, University of KwaZulu Natal, Durban, South Africa where he heads a synthetic and medicinal chemistry research group. His research endeavors have produced over 100 publications in high-impact factor journals of international repute. He has successfully graduated 15 postgraduate students (7 Ph.Ds. and 8 MScs) in research since 2014. He is also a nationally recognized rated researcher by National Research Foundation (South Africa).
