Antibody Engineering

As the field of antibody engineering continues its explosive growth, more and more scientists around the world are striving to keep up with the latest developments. Now in its second edition, Antibody Engineering is the perfect one-stop introduction to state-of-the-art technologies emerging in the field today. In presenting a practical overview of the engineering of recombinant human or mouse monoclonal antibodies, the book incisively addresses essential topics such as antibody structure relevant to engineering, recombinatorial cDNA libraries, phage display, synthetic and humanized antibodies, engineering of affinity and biological effector functions, and plant, mammalian, and bacterial expression vectors and hosts. Antibody Engineering, Second Edition - written by leading experts and now thoroughly updated - is a unique resource for current information on the subject. It will be welcomed by researchers in immunology, biotechnology, molecular biology, and biochemistry.

Summary

This book will help researchers to understand and develop designer antibodies. It provides a practical overview on how to use state-of-the-art technologies in antibody engineering, for the production of recombinant human or mouse monoclonal antibodies. Subjects such as antibody structure relevant to antibody engineering, plant and mammalian expression vectors and hosts, recombinatorial DNA libraries, PCR cloning of single cells, engineering of affinity and biological effector functions, are thoroughly explored by some of the leading experts in each field.

Product details

• Authors: Borrebaeck
• Assisted by: Carl A. Borrebaeck (Editor), Carl A. K. Borrebaeck (Editor)
• Publisher: Oxford University Press
• Languages: English
• Product format: Paperback / Softback
• Released: 18.05.1995
• EAN: 9780195091502
• ISBN: 978-0-19-509150-2
• Dimensions: 234 mm x 160 mm x 25 mm
• Weight: 721 g
• Illustrations: halftones, line figures, tables
• Series: Breakthroughs in Molecular Biology; Breakthroughs in Molecular Bio
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; Immunology, MEDICAL / Immunology, SCIENCE / Life Sciences / Biochemistry, SCIENCE / Biotechnology, SCIENCE / Life Sciences / Molecular Biology, biochemistry, molecular biology, biotechnology