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Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches.
It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.
List of contents
Section 1: Combination drug delivery approaches against various diseases 1. Drug resistance as challenges to effective therapy 2. Overcoming the challenges of drug resistance through combination drug delivery approach 3. Combination drug delivery approaches for pulmonary diseases 4. Combination drug delivery approaches in ophthalmology 5. Combination drug delivery system to enhance the transdermal drug delivery 6. Combination drug delivery approaches in arthritis rheumatoid and osteoarthritis 7. Combination drug delivery approaches for cardiovascular disease 8. Combination drug delivery approaches for viral infection 9. Combination drug delivery approaches for malaria parasite 10. Combination drug delivery approaches for tuberculosis
Section 2: Combination drug delivery approaches against cancer 11. Combination drug delivery approaches for cancer therapy 12. Prodrug-based drug delivery approaches in cancer combination therapy 13. Combination of anticancer drugs with microRNA therapeutics as cancer therapeutics 14. Cocktail chemotherapy by combination drug delivery systems 15. Nanotechnology-mediated combinational drug delivery approach for cancer therapy 16. Combinational chemotherapy and hyperthermia in cancer treatment
Section 3: Combination drug delivery approaches challenges and future perspectives 17. Premarket review and postmarket regulation of combination drug products 18. Challenges associated with nanoparticulate combination drug delivery systems 19. Concluding remarks and future perspective of combination drug delivery systems
About the author
Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.
