Mayo Clinic Cases in Neuroimmunology

Mayo Clinic Cases in Neuroimmunology delivers a case-based walk-through of demyelinating, autoimmune, and other inflammatory neurologic disorders and their mimics. The authors present cases from their own extensive experience with common and rare neuroimmunologic disorders.

The format of this case-based book was developed to stimulate consideration of the differential diagnosis as the reader reviews the history and examination narratives of each of the 83 cases. Videos of autoimmune movement disorders supplement the clinical descriptions, where pertinent. In addition, test results from radiology, electrophysiology, and laboratory studies are presented, and treatment and outcome data are also included. Clinical pearls and radiologic clues to assist informed diagnostic decision-making are emphasized. Each case is followed by discussion, including therapeutic guidance and key take-home points.

More than 150 multiple-choice questions with answers are also given to test readers' comprehension and retention. This new addition to the Mayo Clinic Scientific Press series is a comprehensive volume on neuroimmunology that will stimulate and inform those aiming for clinical mastery.

List of contents

• Section I


• CNS Demyelinating Disease (Cases 1-21)


• Case 1 A Woman With Subacute Painful Vision Loss


• Jiraporn Jitprapaikulsan, MD, M. Tariq Bhatti, MD, Eric R. Eggenberger, DO, and Marie D. Acierno, MD


• Case 2 Rapidly Progressive Numbness and Weakness After Soft-Tissue Abscess


• Elia Sechi, MD, and Dean M. Wingerchuk, MD


• Case 3 Weakness With Neck Flexion


• Brian G. Weinshenker, MD


• Case 4 New-Onset Right-Sided Numbness and Double Vision


• W. Oliver Tobin, MB, BCh, BAO, PhD


• Case 5 Progressive Left Lower Extremity Weakness and Thoracic Spinal Cord Lesion


• B. Mark Keegan, MD


• Case 6 Progressive Spasticity With a Single Magnetic Resonance Imaging Lesion


• Samantha A. Banks, MD, and Eoin P. Flanagan, MB, BCh


• Case 7 Fluctuating Vision Loss, Seizures, and Left Parieto-Occipital Mass


• Alicja Kalinowska-Lyszczarz, MD, PhD, W. Oliver Tobin, MB, BCh, BAO, PhD, Yong Guo, MD, PhD, and Claudia F. Lucchinetti, MD


• Case 8 Diffuse Pain and Abnormal Brain MRI Findings


• Andrew McKeon, MB, BCh, MD


• Case 9 Lesions Found by Chance


• Dean M. Wingerchuk, MD


• Case 10 Encephalopathy and Quadriparesis After an Upper Respiratory Tract Infection


• A. Sebastian Lopez Chiriboga, MD


• Case 11 Severe Monocular Vision Loss Followed by Gait Difficulty


• Brian G. Weinshenker, MD


• Case 12 Multiple Sclerosis and Cognitive Impairment


• Cristina Valencia-Sanchez, MD, PhD, and Jonathan L. Carter, MD


• Case 13 New-Onset Gait Difficulty With Kappa Free Light Chains in Cerebrospinal Fluid


• Maria Alice V. Willrich, PhD, and Ruba S. Saadeh


• Case 14 A Girl With Back Pain, Paresthesias, and Painful Vision Loss


• Cecilia Zivelonghi, MD, and Andrew McKeon, MB, BCh, MD


• Case 15 A Septuagenarian With Progressive Hemiparesis


• Roman Kassa, MD, and B. Mark Keegan, MD


• Case 16 Recurrent Demyelinating Episodes


• I. Vanessa Marin Collazo, MD


• Case 17 Breakthrough Disease While on Multiple Sclerosis Immunomodulatory Therapy


• Jonathan L. Carter, MD


• Case 18 Highly Active Multiple Sclerosis


• Roman Kassa, MD, and W. Oliver Tobin, MB, BCh, BAO, PhD


• Case 19 Progressive Gait Difficulties


• I. Vanessa Marin Collazo, MD


• Case 20 Progressive Cerebellar Ataxia After Natalizumab Treatment


• Michel Toledano, MD


• Case 21 Weakness and Dysarthria After Radiosurgery


• Andr

  About the author

  Andrew McKeon, Mark Keegan, and Oliver Tobin are Mayo Clinic-based neuroimmunologists. They provide care for patients with diverse immune-mediated CNS diseases 'from cortex to c-fibers', including MS, NMO, and paraneoplastic disorders, both in the Multiple Sclerosis and Autoimmune Neurology Clinics, and diagnostic Neuroimmunology Laboratory. Educational accomplishments include being current or former fellowship program directors at Mayo Clinic, and in research have characterized a number of inflammatory CNS diseases (CLIPPERS and Autoimmune GFAP astrocytopathy).

  Summary

  Mayo Clinic Cases in Neuroimmunology delivers a case-based walk-through of demyelinating, autoimmune, and other inflammatory neurologic disorders and their mimics. The authors present cases from their own extensive experience with common and rare neuroimmunologic disorders.
  
  The format of this case-based book was developed to stimulate consideration of the differential diagnosis as the reader reviews the history and examination narratives of each of the 83 cases. Videos of autoimmune movement disorders supplement the clinical descriptions, where pertinent. In addition, test results from radiology, electrophysiology, and laboratory studies are presented, and treatment and outcome data are also included. Clinical pearls and radiologic clues to assist informed diagnostic decision-making are emphasized. Each case is followed by discussion, including therapeutic guidance and key take-home points.
  
  More than 150 multiple-choice questions with answers are also given to test readers' comprehension and retention. This new addition to the Mayo Clinic Scientific Press series is a comprehensive volume on neuroimmunology that will stimulate and inform those aiming for clinical mastery.

  Additional text

  This book is useful for general neurologists for review on the wards and in clinic, as well as neuroimmunologists.

  Report

  This book is useful for general neurologists for review on the wards and in clinic, as well as neuroimmunologists. Tzu-Ying Chuang, MD, PhD, (Thomas Jefferson University), DOODY'S

Product details

• Authors: McKeon , B Mark Keegan, B. Mark Keegan, B. Mark (Professor of Neurology Keegan, Keegan B. Mark, Andrew McKeon, Andrew (Professor of Laboratory Medicine & Mckeon, Andrew (Professor of Laboratory Medicine & Pathology and of Neurology McKeon, W Oliver Tobin, W. Oliver Tobin, W. Oliver (Associate Professor of Neurology Tobin
• Publisher: Oxford University Press
• Languages: English
• Product format: Paperback / Softback
• Released: 31.12.2021
• EAN: 9780197583425
• ISBN: 978-0-19-758342-5
• No. of pages: 322
• Dimensions: 218 mm x 280 mm x 13 mm
• Series: Print on Demand; Mayo Clinic Scientific Press; MAYO CLINIC SCIENTIFIC PRESS SERIES
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; Immunology, MEDICAL / Immunology, MEDICAL / Neuroscience, MEDICAL / Neurology, Neurology & clinical neurophysiology, Oncology, Neurology and clinical neurophysiology