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Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials. This succinct reference focuses on the current data and research on diabetic neuropathy and is essential reading for researchers in endocrinology, neurology and pharmacology, along with clinicians that need to better understand the novel pathogenetic pathways leading to diabetic neuropathy and the treatments.
List of contents
1. Classification, risk factors, and symptoms of diabetic neuropathy
Dilek Gogas Yavuz
2. Pathologic basis of diabetic neuropathy in humans
Soroku Yagihashi
3. Electrodiagnostic evaluation in diabetic neuropathy
Deepak Menon and Vera Brill
4. Advances in screening, early diagnosis and accurate staging of diabetic neuropathy
Josie Carmichael, Hassan Fadavi, Fukashi Ishibashi, Angela Shore, and Mitra Tavakoli
5. Skin Biopsy and Diabetic Neuropathy
Páll Karlsson
6. Central Nervous System Involvement in Painful Diabetic Neuropathy
Joyce Lim, Solomon Tesfaye, and Dinesh Selvarajah
7. Spinal Cord Involvement in Diabetic Neuropathy and Neuropathic Pain
Andrew Marshall, Anne Marshall, and Nigel A. Calcutt
8. The conundrum and enigma of painful and painless neuropathy
Johan Røikjer and Niels Ejskjaer
9. Motor Dysfunction in Diabetes
Anders Mark Sandbergh Stouge and Henning Andersen
10. Diabetic Autonomic Neuropathy: Measurement and Management, Part 1: Measurement
Joe Colombo
11. Diabetic neuropathy in children and youth
Gulcin Akinci, Masha G. Savelieff, Gary Gallagher, Brian C. Callaghan, and Eva L. Feldman
12. Treatment-Induced Painful Diabetic Neuropathy
Milla Rosengard-Barlund and Hanna Harno
13. Costs of Diabetic Neuropathy and Diabetic Foot
Beatriz Rodriguez-Sanchez and Alan Sinclair
14. Diabetic Foot
Frank Lee Bowling, Keeley J. Foley, and Andrew J. M. Boulton
15. Management of Diabetic Foot Disease
Prashta R J Vas and Venu Kavarthapu
16. Strategies for the Prevention or Reversal of Neuropathy
Lindsay A. Zilliox, Krish Chandrasekaran, and James W. Russell
17. Treatment of diabetic peripheral neuropathy: technologies, exercise and alternative treatments
Kalliopi Pafili and Nikolaos Papanas
18. Treatment of Diabetic Polyneuropathy
Amanda C. Peltier
19. Diabetic Autonomic Neuropathy: Measurement and Management, Part II: Management
Joe Colombo
20. Translating a Treatment for Diabetic Peripheral Neuropathy from Rodents to Humans: Can a Case be made for Fish Oil and Salsalate?
Mark Yorek
21. Bedside Clinical Features and Translational Snapshots of Diabetic Polyneuropathy
Brendan N. Putko and Douglas W. Zochodne
About the author
Professor Mitra Tavakoli is Associate Professor of Medicine at the University of Exeter and is distinguished for her significant contribution to our understanding of the small fibre neuropathy at diabetes and establishing the technique of “Corneal Confocal Microscopy”. She is an internationally recognised researcher in diabetes care, with a significant focus on innovation and bringing new ideas to the field.
Her recent work elucidated the role of intervention for the regeneration of nerves at type 1 and type 2 diabetes. Her ongoing research into understanding the role of novel intervention at rare models of neuropathies, which initiated a new direction of research.
Dr Tavakoli has been the lead investigator in several national and international multisite clinical trials and a Chief Investigator in major clinical trials. Her research is funded mainly by Industry, National Institute of Health Research (NIHR), National Institute of Health (NIH). She has published over 75 peer-reviewed scientific papers and textbook chapters and in excess of 100 abstracts. She regularly speaks at international and national conferences and meetings. In addition, she is widely respected for training scientists across the world. She spearheads new technologies and contributes to the major UK and international collaborations.
