Handbook on Opium - History and Basis of Opioids in Therapeutics

Handbook of Opium: History and Basis of Opioids in Therapeutics traces the history of poppy from its prehistory, its use in Greek and Egyptian medicine through the European Renaissance, and the opioid epidemic of the present day. The book explores the discovery of morphine and its alkaloids, reviews its biosynthetic process, and covers the evolution of synthetic opioids. Further, it reviews the biological effects of opium and the molecular basis of its actions, including future perspectives in clinical applications with therapeutic targets. The book is interspersed with numerous notes on the events and great minds in history and medicine who advocated, analyzed and advanced opium through history.
The book is a comprehensive review on opium, covering a breadth of topics, including its history, botany, chemistry, trade, physiology, clinical use and molecular biology, with numerous references, tables, vignettes and illustrations included for additional understanding.

List of contents

Section 1 - History: From Cotyledons to Capsules

Part I: Plant
1. Botanical Aspects

Part II: History
2. Pre-History
3. Ancient History
4. Post-Classical History
5. Modern History
6. Contemporary History

Part III. Trade
7. Business of Opium

Section 2 - Basis of Opioids in Therapeutics: Receptors, Effectors and Beyond

Part IV: Alkaloids
8. Opiates
9. Opioids

Part V: Molecular Basics
10. Receptors
11. Effectors

Part VI: Effects
12. Biological Effects
13. Mechanisms
14. Clinical Uses and Issues

Part VII: The Future
15. Outlook

Epilogue
Index

About the author

Dr. Vasantha K Kumar, MD is a currently a practicing anesthesiologist at Mercy Health, located in Cincinnati, OH. Board certified in Pain Medicine and Anesthesiology (American Board of Anesthesiology), he has been practicing for 20 years and has published over 70 peer reviewed journal papers and presentations. He is a member of the American Medical Association, the American Society of Anesthesiologists, Spine Intervention Society, and American Society of Regional Anesthesia.

Product details

• Authors: Vasanth Kumar, Vasanth (Anesthesiologist Kumar
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Paperback / Softback
• Released: 31.01.2022
• EAN: 9780323909037
• ISBN: 978-0-323-90903-7
• No. of pages: 244
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; SCIENCE / Life Sciences / General, PHYSIOLOGY, SCIENCE / Life Sciences / Biology, MEDICAL / Anesthesiology, Pharmacology, Poppy; opioids; pain; opioid receptors; medical history