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Utilizing clinical case material of children with diabetes insipidus (DI), this concise, practical pocket guide will provide clinicians with the best real-world strategies to properly diagnose and manage the various manifestations of the disorder they may encounter. It presents a detailed cross-section of pediatric patients, with different etiologies of the disease and possible complications, to provide sensible management scenarios to physicians treating patients with DI. The cases presented include diagnostic strategies and radiological findings for familial and nephrogenic DI as well as DI resulting from hypophysitis, germ cell tumors, Rathkes Cleft Cysts, Langerhans Cell Histiocytosis, craniopharyngiomas, genetic causes, and congenital malformations. Each case focuses on a specific learning objective with clinical pearls, and together these cases represent a comprehensive understanding of children with DI from many aspects.
Managing pediatric patients with DI isa threefold challenge of determining the diagnosis, etiology and treatment. Pragmatic and reader-friendly, Diabetes Insipidus in Children is an excellent resource to assist endocrinologists and other clinicians caring for patients with this disease.
List of contents
Primary Polydipsia.- Diagnosing DI (Water Deprivation).- MRI Lesions in Diabetes Insipidus.- Central Diabetes Insipidus with Pituitary Stalk Thickening.- Hypophysitis.- Germ Cell Tumors.- The Gist of a Rathke's Cleft Cyst.- Langerhans Cell Histiocytosis and Diabetes Insipidus.- Craniopharyngioma and Diabetes Insipidus.- Diabetes Insipidus after Craniopharyngioma Resection.- Partial Central Diabetes Insipidus Following Endonasal Biopsy.- Septo-optic Dysplasia Spectrum.- Familial Diabetes Insipidus.- Treatment with Thiazides in Infants with Central Diabetes Insipidus.- Absent Thirst and Diabetes Insipidus.- Nephrogenic Diabetes Insipidus.
About the author
Craig A. Alter, MD, Director, Neuroendocrine Center, Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA
