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¿The study of stem cell biology is under intensive investigation. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell and gene therapy.
The aim of this book is to provide readers and researchers with timely and accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on conferences given by recognized scientists involved in the international master course on stem cell biology at Sorbonne Université in Paris.
List of contents
1 Stem Cell Concepts 2 Transcription Regulation by Distal Enhancers: Dynamics of the 3D Genome 3 Repair of DNA Double-Strand Breaks in Adult Stem Cells 4 Haematopoietic Stem Cell Niches in the Bone Marrow 5 Computational Models of Spatio-temporal Stem Cell Organization 6 Transcriptomics Investigations 7 The Regulatory Network of X Chromosome Inactivation 8 Directed Differentiation of Human-induced Pluripotent Stem Cells into Hepatic Cells: A Transposable Example of Disease Modeling and Regenerative Medicine Applications 9 Hydra and the Evolution of Stem Cells 10 Regeneration in Anamniotic Vertebrates 11 Stem Cells and Regeneration in Plants 12 Hematopoietic Development in Vertebrates 13 Developmental Biology of Hematopoietic Stem Cells: Non-cell Autonomous Mechanisms 14 Biology of Hematopoietic Stem Cells in the Adult 15 Epithelial Stem Cells in the Skin 16 Mammary Stem Cells 17 The Intestinal Stem Cells in Homeostasis and Repair 18 Neural Stem Cells 19 Non-hematopoietic Stem Cells of Bone and Bone Marrow 20 Dental Stem Cells 21 Stem Cells and Retina: From Regeneration 22 Glioblastoma Stem Cells 23 Cardiac Tissue Engineering for Repair and Regeneration of the Heart 24 Stem Cells for Red Blood Cell Production 25 Prospectives for Therapy With Stem Cells in Skeletal Muscular Diseases 26 Legal Framework for Research on Human Embryonic Stem Cells in France and in Europe 27 Stem Cell Conceptual Clarifications 28 Future Outlook
About the author
Charles Durand, Pierre Charbord
Summary
The study of stem cell biology is under intensive investigation. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell and gene therapy.
The aim of this book is to provide readers and researchers with timely and accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on conferences given by recognized scientists involved in the international master course on stem cell biology at Sorbonne Université in Paris.
