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Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.
This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.
List of contents
1. Bone multiscale mechanics 2. Bone remodeling biology 3. Bone diseases and associated therapeutic solutions 4. Bone remodeling mathematical models 5. Bone and bone remodeling finite element modeling 6. Bone remodeling: Analysis, discussion and perspectives
About the author
Rabeb BEN KAHLA is a Mechanical Engineering PhD student at the National Engineering School of Tunis, Tunisia. She conducts research at LASMAP (Research Laboratory of Systems and Applied Mechanics) of Tunisia Polytechnic School. Currently assistant teacher at Ecole d'Ingénieurs Généraliste du Numérique (Efrei PARIS), France, she is the author of the book “Finite element method and medical imaging techniques in bone biomechanics” (Wiley ISBN: 978-1-786-30518-3) and three publications in well-known journals in the field of biomechanics (Journal of the Mechanical Behavior of Biomedical Materials, Biomechanics and Modeling in Mechanobiology , Journal of Mechanics in Medicine and Biology).Abdelwahed Barkaoui is a Full Professor of Mechanical Engineering at the International University of Rabat, Morocco. He is currently the head of the Mechanical and Advanced Materials Division at the LERMA Laboratory and the coordinator of the Biomechanics and Mechanobiology Research Team (MeV). Additionally, he is responsible for the international accreditation at the College of Engineering and Architecture. His research primarily focuses on problems in biomechanics, mechanobiology, and biomedical engineering.
