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This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.
List of contents
1.Human Papillomavirus-associated cancers.- 2. Mechanisms of immune evasion by Ebola virus.- 3. Innate immune mechanisms against HIV-1.- 4. Current insights into the host immune response to respiratory viral infections.- 5. Immune responses to MERS-CoV in humans and animals.- 6. SARS-CoV-2: Pathogenesis and host-pathogen interaction.- 7. Antibiotic Resistance mechanisms and their transmission in Acinetobacter baumannii.- 8. Pathogenesis and host immune response in leprosy.- 9. Innate immunity and tuberculosis.- 10. Vaccination strategies against Mycobacterium tuberculosis: BCG and beyond.- 11. Candida pathogenicity and interplay with the immune system.- 12. Immune responses in Malaria and vaccine strategies.
About the author
Uday Kishore is a teacher and a scientist with special interest in innate immunity. He was the Founder Director of the Centre for Infection, Immunity and Disease Mechanisms, Brunel University London. He earned his BSc from S.P. Jain College, Sasaram, Bihar, India; MSc from Hindu College, Delhi; and PhD from the Department of Zoology, University of Delhi and CSIR Institute of Genomics and Integrative Biology, Delhi, India. After spending a year at the Salk Institute for Biological Studies, La Jolla, California, he moved to the University of Oxford for the major part of his post-doctoral training, first at the MRC Immunochemistry Unit, Department of Biochemistry, and then at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital. His is the recipient of fellowships of NASA (USA), Wellcome Trust (UK) and Alexander Humboldt Foundation (Germany), MRC Investigator Prize, European Commission Young Scientist Prize, and Mother Teresa Excellence Award. Uday Kishore holds severaladjunct, visiting and honorary professorial positions nationally and internationally. He has altogether authored over 200 research papers, book chapters, patents, and books. His research focuses on how C-type lectins (especially collectins such as surfactant protein D) and individual complement proteins (C1q, factor H and properdin) resist a range of pathogens such as HIV-1, SARS-CoV-2, Influenza A Virus, Mycobacterium tuberculosis, Aspergillus fumigatus and Plasmodium falciparum.
