Organofluorine Chemistry - Synthesis, Modeling, and Applications

By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

List of contents

1. The Development of New Reagents and Reactions for Synthetic Organofluorine Chemistry by Understanding the Unique Fluorine Effects
2. Perfluoroalkylation Using Perfluorocarboxylic Acids and Anhydrides
3. Chemistry of OCF3, SCF3, and SeCF3 Functional Groups
4. Introduction of Trifluoromethylthio Group into Organic Molecules
5. Bifunctionalization-Based Catalytic Fluorination and Trifluoromethylation
6. Fluorination, Trifluoromethylation, and Trifluoromethylthiolation of Alkenes, Cyclopropanes, and Diazo Compounds
7. Photoredox Catalysis in Fluorination and Trifluoromethylation Reactions
8. Asymmetric Fluorination Reactions
9. The Self-Disproportionation of Enantiomers (SDE): Fluorine as an SDE-Phoric Substituent
10. DFT Modeling of Catalytic Fluorination Reactions: Mechanisms, Reactivities, and Selectivities
11. Current Trends in the Design of Fluorine-Containing Agrochemicals
12. Precision Radiochemistry for Fluorine-18 Labeling of PET Tracers

About the author

Kálmán J. Szabó is professor at the Department of Organic Chemistry at the Arrhenius Laboratory, Stockholm University (Sweden), since 2003. His major research interests are method development in organic synthesis, catalytic reactions, organoboron and organofluorine (including fluorine-18) chemistry. He is a member of the Royal Swedish Academy of Sciences and has authored over 150 publications. He is the editor of the book "Pincer and Pincer-Type Complexes" (Wiley-VCH).
 
Nicklas Selander is an assistant professor at the Department of Organic Chemistry at Stockholm University (Sweden), since 2018. His research interests include organic synthesis methodology, catalysis, and radical chemistry.

Product details

• Authors: Nicklas Selander, Kálmán J. Szabó
• Assisted by: Kálmá J Szabó (Editor), Kálmán J Szabó (Editor), Selander (Editor), Selander (Editor), Nicklas Selander (Editor), Kálmán J. Szabó (Editor)
• Publisher: Wiley-VCH
• Languages: English
• Product format: Hardback
• Released: 27.01.2021
• EAN: 9783527347117
• ISBN: 978-3-527-34711-7
• No. of pages: 448
• Dimensions: 176 mm x 26 mm x 250 mm
• Weight: 1002 g
• Illustrations: 397 SW-Abb., 97 Farbabb., 39 Tabellen
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Organic chemistry; Chemie, Organische Chemie, ORGANIC CHEMISTRY, Katalyse, chemistry, Catalysis, Biomedical engineering, Pharmaceutical & Medicinal Chemistry, Pharmazeutische u. Medizinische Chemie, Bildgebende Verfahren i. d. Biomedizin, Biomedical Imaging, Biomedizintechnik