Fr. 93.60

A Tale of Two Viruses - Parallels in the Research Trajectories of Tumor and Bacterial Viruses

English · Hardback

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Description

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"In 1965, French microbiologist Andrâe Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny-one of the two types of viral life cycles-which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses-bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer-and the importance of Lwoff's discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell's genetic material indefinitely, or until induced by UV radiation. But until Lwoff's discovery of the mechanism of lysogeny, microbiologist Fâelix d'Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices"--

About the author










Neeraja Sankaran is a historian of science and medicine with a primary focus in the recent and near-contemporary history of biomedical sciences. An independent scholar, she has held positions at universities in different parts of the world, including the United States, Egypt, South Korea, India, the United Kingdom, and the Netherlands.

Summary

The first study of medical virology to compare the history of bacteriophages and sarcoma agents.

Product details

Authors Neeraja Sankaran
Publisher University Of Pittsburgh Press
 
Languages English
Product format Hardback
Released 30.04.2021
 
EAN 9780822946304
ISBN 978-0-8229-4630-4
No. of pages 312
Dimensions 150 mm x 231 mm x 30 mm
Weight 612 g
Subject Natural sciences, medicine, IT, technology > Natural sciences (general)

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