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Zusatztext The text is vivid! the pictures are appropriate! and the text is well written. ? [A] good resource on sleep. This is an important book for neuroscience and neurology libraries for its usefulness in both fields. It should be a certain acquisition for those libraries.-Doody's Informationen zum Autor Pierre-Herve' Luppi Klappentext This comprehensive book discusses the major discoveries related to the circuits responsible for slow wave sleep (SWS)! rapid eye movement (REM) sleep! narcolepsy! and the possible role of sleep in memory and developmental processes. It also presents recent advances in sleep research obtained by means of emerging technologies. Sleep: Circuits and Functions includes new data obtained by differential gene expression analysis! transgenic mice! and functional imaging as well as new theoretical concepts on the mechanisms regulating sleep. Zusammenfassung An estimated 40 million Americans and millions of others worldwide suffer from some type of sleep disruption or disorder, and these numbers are rapidly increasing. As biomedical technologies advance our understanding of sleep, a wave of developments in sleep research and the emergence of new technologies offer hope and help for a good night’s sleep. Sleep: Circuits and Functions discusses the major discoveries related to the circuits responsible for slow wave sleep, REM sleep, narcolepsy, and the possible role of sleep in memory and developmental processes. World-renowned researcher Pierre-Hervé Luppi and a panel of expert contributors highlight advances in sleep research obtained by means of promising technologies. Data obtained by differential gene expression analysis, transgenic mice, and functional imaging is presented, as well as theoretical concepts on the mechanisms regulating sleep. Updating our knowledge of the strides made in sleep research, this comprehensive book also identifies future research opportunities in this growing field. It is an essential resource for medical professionals and researchers who aim to finally put sleep disorders to bed. Inhaltsverzeichnis NEURONAL NETWORKS RESPONSIBLE FOR THE SLEEP-WAKING CYCLE. Sleep and Neuronal Plasticity: Cellular Mechanisms of Corticothalamic Oscillations. Role of Extra-Thalamic Pathways in Sleep and the EEG Oscillations. In Vitro Identification of the Presumed Sleep-promoting Neurons of the Ventrolateral Preoptic nucleus (VLPO). Molecular Mechanisms of Sleep-wake Regulation: A Role of Prostagliandin D2 and Adenosine. The Network Responsible for Paradoxical Sleep Onset and Maintenance: A New Theory Based on the Head-restrained Rat Model. Reverse Genetics and the Study of Sleep/Wake Cycle: The Hypocretins and Cortistatin. Genetic Regulation of Sleep. Searching for Sleep Mutants of Drosophila Melanogaster. FUNCTIONS OF SLEEP. Sleep Phylogeny: Clues of the Evolution and Function of Sleep. Sleep, Synaptic plasticity and the Developing Brain. Changes in Brain Gene Expression Between Sleep and Wakefulness. Neuronal Reverberation and the Consolidation of New Memories Across the Wake-Sleep Cycle. Cerebral Functional Segregation and Integration During Human Sleep. ...
