Portable Spectroscopy and Spectrometry, Technologies and - Instrumentatio

Provides complete and up-to-date coverage of the foundational principles, enabling technologies, and specific instruments of portable spectrometry
 
Portable Spectroscopy and Spectrometry: Volume One is both a timely overview of the miniature technologies used in spectrometry, and an authoritative guide to the specific instruments employed in a wide range of disciplines. This much-needed resource is the first comprehensive work to describe the enabling technologies of portable spectrometry, explain how various handheld and portable instruments work, discuss their potential limitations, and provide clear guidance on optimizing their utility and accuracy in the field. In-depth chapters--written by a team of international authors from a wide range of disciplinary backgrounds--have been carefully reviewed both by the editors and by third-party experts to ensure their quality and completeness.
 
Volume One begins with general discussion of portable spectrometer engineering before moving through the electromagnetic spectrum to cover x-ray fluorescence (XRF), UV-visible, near-infrared, mid-infrared, and Raman spectroscopies. Subsequent chapters examine microplasmas, laser induced breakdown spectroscopy (LIBS), nuclear magnetic resonance (NMR) spectroscopy, and a variety of portable mass spectrometry instrument types. Featuring detailed chapters on DNA instrumentation and biological analyzers--topics of intense interest in light of the global coronavirus pandemic--this timely volume:
* Provides comprehensive coverage of the principles and instruments central to portable spectroscopy
* Includes contributions by experienced professionals working in instrument companies, universities, research institutes, the military, and hazardous material teams
* Discusses special topics such as smartphone spectroscopy, optical filter technology, stand-off detection, and MEMS/MOEMS technology
* Covers elemental spectroscopy, optical molecular spectroscopy, mass spectrometry, and molecular and imaging technologies
 
Portable Spectroscopy and Spectrometry: Volume One is an indispensable resource for developers of portable instruments, civilian and government purchasers and operators, and teachers and students of portable spectroscopy. When combined with Volume Two, which focuses on the multitude of applications of portable instrumentation, Portable Spectroscopy and Spectrometry provides the most thorough coverage of the field currently available.

List of contents

List of Contributors xiii
 
Foreword xvii
 
Preface for Volume 1 xix
 
Acknowledgements xxi
 
1 Introduction to Portable Spectroscopy 1
Pauline E. Leary, Richard A. Crocombe and Brooke W. Kammrath
 
1.1 Introduction 1
 
1.2 Defining Portable Spectrometers 1
 
1.3 Performance 2
 
1.4 History and Availability 4
 
1.5 Instrument Design and Enabling Technologies 7
 
1.6 Producing Results 8
 
1.7 Outline of These Volumes 9
 
Acronyms and Abbreviations 11
 
References 12
 
2 Engineering Portable Instruments 15
Terry Sauer
 
2.1 Size/Weight 15
 
2.2 Sample Interface 16
 
2.3 Embedded Computer vs. External Personal Computer (PC) 16
 
2.4 Reduced Feature Set 17
 
2.5 Target of Non-Spectroscopist 17
 
2.6 Power Budget 18
 
2.7 Voltage Conversion 18
 
2.8 Decon/Ingress Protection (IP) Rating 19
 
2.9 Testing the Seal 20
 
2.10 Gloved Operation 20
 
2.11 Display 21
 
2.12 Thermal Concerns 23
 
2.13 Optical Elements 27
 
2.14 Interferometer Optical Design 27
 
2.15 Interferometer Bearings 29
 
2.16 Vibration 30
 
2.17 Shock 30
 
2.18 Battery 31
 
2.19 Electrostatic Discharge (ESD) 32
 
2.20 Ergonomics 34
 
2.21 Laser Safety 34
 
2.22 Stability 35
 
2.23 Service 38
 
2.24 Communications/Wireless 38
 
References 38
 
3 Design Considerations for Portable Mid-Infrared FTIR Spectrometers Used for In-Field Identifications of Threat Materials 41
David W. Schiering and John T. Stein
 
3.1 Introduction and Background 41
 
3.2 FTIR System Components 44
 
3.3 FTIR Spectrometer Performance Attributes 53
 
3.4 Modeling and Simulation Guide to Portable Instrument Design and Development 55
 
3.5 Portable FTIR Performance Benchmarks 60
 
3.6 Conclusion 62
 
Abbreviations and Acronyms 62
 
References 63
 
4 PAT Applications of NIR Spectroscopy in the Pharmaceutical Industry 67
Pierre-Yves Sacré, Charlotte De Bleye, Philippe Hubert and Eric Ziemons
 
4.1 Introduction 67
 
4.2 Continuous Manufacturing and Real-Time Release Testing 67
 
4.3 PAT Implementation of Near-Infrared Spectroscopy 73
 
4.4 Conclusion 79
 
Glossary 81
 
References 82
 
5 MOEMS and MEMS - Technology, Benefits & Uses 89
Heinrich Grüger
 
5.1 Introduction 89
 
5.2 Grating-Based Spectrometers 92
 
5.3 Fourier Transform Spectrometer 101
 
5.4 Tunable Fabry-Perot Interferometer 104
 
5.5 Integration Strategies for MEMS-/MOEMS-Based Spectrometers 106
 
5.6 Use of MEMS-Based NIR Spectrometers 108
 
Acronyms and Abbreviations 109
 
References 110
 
6 Portable Raman Spectroscopy: Instrumentation and Technology 115
Cicely Rathmell, Dieter Bingemann, Mark Zieg and David Creasey
 
6.1 Introduction 115
 
6.2 The Case for Raman: Capabilities and Scope 115
 
6.3 The Theory of Raman Spectra 116
 
6.4 Basics of a Raman System 119
 
6.5 "Portable" Versus "Handheld" Versus "Mini" 119
 
6.6 Performance Needs in Portable Raman Instruments 120
 
6.7 Excitation Laser 122
 
6.8 Optical Filters and Sampling Optics 125
 
6.9 Spectrometer Design 127
 
6.10 Sample Interface and Accessories 134
 
6.11 Spectral Processing and Analysis 135
 
6.12 Special Cases 138
 
6.13 Conclusion 140
 
Acronyms and Abbreviations 141
 
References 141

About the author

RICHARD A. CROCOMBE, PHD, operates Crocombe Spectroscopy Consulting, served as the 2020 President of the Society for Applied Spectroscopy (SAS), and is Chair of the SPIE 'Next¿Generation Spectroscopic Technologies' conference. He has 40 years of experience in the analytical instrumentation business. For the last 15 years, he has specialized in miniature and portable spectrometers.
PAULINE E. LEARY, PHD, is a Reachback Chemist at Federal Resources where she specializes in miniature and portable spectrometers and instrument platforms. For over 15 years, she has been training users, including field scientists, emergency responders, and conventional and specialized forces of the United States military, on the theory and operation of portable systems. Pauline has presented on portable instruments at conferences and technical symposia throughout the world.
BROOKE W. KAMMRATH, PHD, is the Assistant Director of the Henry C. Lee Institute of Forensic Science and an Associate Professor in the Forensic Science Department of the Henry C. Lee College of Criminal Justice and Forensic Sciences at University of New Haven. She also serves as a scientific consultant and expert witness for both criminal and civil cases. She served as the President of the New York Microscopical Society (NYMS) from 2017-2019, is on the Governing Board of the Eastern Analytical Symposium (EAS), and is a Diplomate of the American Board of Criminalistics (ABC).

Summary

Provides complete and up-to-date coverage of the foundational principles, enabling technologies, and specific instruments of portable spectrometry

Portable Spectroscopy and Spectrometry: Volume One is both a timely overview of the miniature technologies used in spectrometry, and an authoritative guide to the specific instruments employed in a wide range of disciplines. This much-needed resource is the first comprehensive work to describe the enabling technologies of portable spectrometry, explain how various handheld and portable instruments work, discuss their potential limitations, and provide clear guidance on optimizing their utility and accuracy in the field. In-depth chapters--written by a team of international authors from a wide range of disciplinary backgrounds--have been carefully reviewed both by the editors and by third-party experts to ensure their quality and completeness.

Volume One begins with general discussion of portable spectrometer engineering before moving through the electromagnetic spectrum to cover x-ray fluorescence (XRF), UV-visible, near-infrared, mid-infrared, and Raman spectroscopies. Subsequent chapters examine microplasmas, laser induced breakdown spectroscopy (LIBS), nuclear magnetic resonance (NMR) spectroscopy, and a variety of portable mass spectrometry instrument types. Featuring detailed chapters on DNA instrumentation and biological analyzers--topics of intense interest in light of the global coronavirus pandemic--this timely volume:
* Provides comprehensive coverage of the principles and instruments central to portable spectroscopy
* Includes contributions by experienced professionals working in instrument companies, universities, research institutes, the military, and hazardous material teams
* Discusses special topics such as smartphone spectroscopy, optical filter technology, stand-off detection, and MEMS/MOEMS technology
* Covers elemental spectroscopy, optical molecular spectroscopy, mass spectrometry, and molecular and imaging technologies

Portable Spectroscopy and Spectrometry: Volume One is an indispensable resource for developers of portable instruments, civilian and government purchasers and operators, and teachers and students of portable spectroscopy. When combined with Volume Two, which focuses on the multitude of applications of portable instrumentation, Portable Spectroscopy and Spectrometry provides the most thorough coverage of the field currently available.

Product details

• Authors: Crocombe, Ra Crocombe, Richard A. Crocombe, Richard A. Leary Crocombe, Brooke Kammrath, Brooke W. Kammrath, Pauline E. Leary
• Assisted by: Richard A. Crocombe (Editor), Crocombe Richard A. (Editor), Paulin E Leary (Editor), Pauline E Leary (Editor), Brooke W. Kammrath (Editor), Pauline E. Leary (Editor), Brooke W Kammrath (Editor)
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 28.02.2021
• EAN: 9781119636366
• ISBN: 978-1-119-63636-6
• No. of pages: 608
• Series: Portable Spectroscopy and Spectrometry
• Subjects: Natural sciences, medicine, IT, technology > Chemistry; Chemie, Spektroskopie, chemistry, spectroscopy, Industrial Chemistry, Technische u. Industrielle Chemie, Pharmaceutical & Medicinal Chemistry, Pharmazeutische u. Medizinische Chemie, Spektrometrie