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Informationen zum Autor Dr. Tollefsbol is a Distinguished Professor at the University of Alabama at Birmingham. He holds doctorates in molecular biology and osteopathic medicine, trained with National Academy of Science members and has over 200 peer-reviewed publications. Reports highlighting the translatability to the lay public of the discoveries made in his laboratory have appeared in international media representing >50 million readers. Dr. Tollefsbol has been featured as an Investigator in the Spotlight by the NIH as well as a Scientist in the Spotlight by ScienceNow. He is an Associate Editor for Frontiers in Genetics , a contributor to Lewin’s GENES classic textbook and Lead Editor for Elsevier’s Translational Epigenetics Series . Dr. Tollefsbol has been named a “Highly Ranked Scholar? worldwide ( ScholarGPS ). He has been invited for numerous endowed keynote presentations, his research has been highlighted in eScience News and ScienceDaily and he has published 20 scholarly books on topics related to his research. Klappentext "Includes contributions by leading international investigators involved in epigenetic research and clinical and therapeutic application Integrates technology and translation with fundamental chapters on epigenetics methods, as well as chapters on more novel and advanced epigenetics methods Written at verbal and technical levels that can be understood by scientists and students alike Includes chapters on state-of-the-art techniques such as single-cell epigenomics, use of CRISPR/Cas9 for epigenetic editing, and epigenetics methods applied to forensics"-- Inhaltsverzeichnis 1. Modelling candidate genes vs genetic variants 2. Disease in a dish: Cellular models to understand human conditions 3. The Yeast, a versatile model system to study human disease 4. The worm, how can it help? 5. Understanding human genetic disease with the fly 6. The fish as a model for human diseases 7. The mouse model 8. Large animal models of rare genetic disorders 9. Crisper/Cas technology 10. Integrative modeling and novel technologies in human genomics...
