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Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment.
List of contents
1. Cancer biology and other disorders: beneficial role of camptothecin and novel derivatives
2. Camptothecin: chemistry, biosynthesis, analogs, and chemical synthesis
3. Camptothecin and analogs: role in anticancer activities
4. Botany of camptothecin-yielding plants
5. Propagation of camptothecin biosynthesizing plants
6. In vitro camptothecin production from plants: prospects and challenges
7. Biomining of camptothecin producing plants through molecular techniques
8. Endophytes and camptothecin production
About the author
Professor T. Pullaiah is a former Professor at the Department of Botany at Sri Krishnadevaraya University in Andhra Pradesh, India, where he has taught for more than 35 years. He was President of Indian Botanical Society (2014), President of the Indian Association for Angiosperm Taxonomy (2013). He was awarded the Panchanan Maheshwari Gold Medal, the Prof. P.C.Trivedi Medal, the Dr. G. Panigrahi Memorial Lecture award of the Indian Botanical Society and Prof. Y.D. Tyagi Gold Medal of the Indian Association for Angiosperm Taxonomy. Under his guidance 54 students obtained their doctoral degrees. He has authored 52 books, edited 23 books and published over 330 research papers, including reviews and book chapters. He was also a member of Species Survival Commission of the International Union for Conservation of Nature (IUCN). Professor Pullaiah received his PhD from Andhra University, India, attended Moscow State University, Russia, and worked as Post-Doctoral Fellow