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"Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems, Volume Two examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects. This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders. This level of discussion makes it a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about the status of drug delivery systems"--
List of contents
1. Solid lipid nanoparticles (SLN): prediction of toxicity, metabolism, fate and physicochemical properties
J.R. CAMPOS, P. SEVERINO, A. SANTINI, A.M. SILVA, RANJITA SHEGOKAR, S.B. SOUTO, AND E.B. SOUTO
2. Role of nanocarriers and their surface modification in targeting delivery of bioactive compounds
HENI RACHMAWATI, ATSARINA LARASATI, ANNIS CATUR ADI, AND RANJITA SHEGOKAR
3. Polymeric nanomicelles as versatile tool for multidrug delivery in chemotherapy
KOBRA ROSTAMIZADEH AND VLADIMIR P. TORCHILIN
4. Nanoparticulate systems for wound healing
MAHA NASR, RIHAM I. EL-GOGARY, HEND ABD-ALLAH, AND MONA ABDEL-MOTTALEB
5. Solid dispersions: technologies used and future outlook
N.B. JADAV AND A. PARADKAR
6. Nanotoxicity: the impact of increasing drug bioavailability
JUAN BUENO
7. Nanoparticle-based vaccines: opportunities and limitations
DIANA DIAZ-ARÉVALO AND MINGTAO ZENG
8. Lipid nanocarriers for delivery of poorly soluble and poorly permeable drugs
ANÐELKA B. KOVACEVIC
9. Nose-to-brain drug delivery: an alternative approach for effective brain drug targeting
AMIT ALEXANDER, MUKTA AGRAWAL, MAHAVIR BHUPAL CHOUGULE, SHAILENDRA SARAF, AND SWARNLATA SARAF
10. Trends in the intellectual property (IP) landscape of drug delivery systems: 30 years of growth and evolution
AMANDA STARLING-WINDHOF, ASUR SRINIVASAN, TINA TOMEO, ANNE MARIE CLARK, AND PETER MATTEI
About the author
Ranjita Shegokar holds a Ph.D. degree in Pharmaceutical Technology from the SNDT University, India, and has been a postdoctoral researcher in the Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics at the Free University of Berlin, Germany. Currently, she serves as Chief Scientific Officer (CSO) at Capnopharm GmbH, Germany. She has authored several research articles, book chapters, and presented her research in many national/international conferences. She has filed multiple patent applications in the area of drug delivery and targeting. Besides that, she has edited many trending books in the area of pharmaceutical nanotechnology and drug delivery aspects. For her research, she has received many prestigious national and international awards among them include recently received prestigious German Innovation Award 2022. Her areas of interest include polymeric nanoparticles, nanocrystals, lipid nanoparticles (SLNs/NLCs), nanoemulsions, cancer drug targeting and the role of excipients in delivery systems. (www.ranjitas.com)
