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-Softcover reprint of a successful hardcover reference (370 copies sold)
-Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering
-Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology
List of contents
From the contents: I. The Functional Properties of Native Tissues.- II. Functional Requirements of Engineered Tissues.- III. Design Parameters for Tissue Engineering.- IV. Assessment of Function in Engineered Tissues.- V. Cell-matrix Interactions in Functional Tissue Engineering.- VI. Bioreactors and the Role of Biophysical Stimuli in Tissue Engineering.- VII. Regulatory and Clinical Issues in Tissue Engineering.
Summary
Tissue engineering is an exciting new field at the interface of engineering and - ology that uses implanted cells, scaffolds, DNA, proteins, protein fragments, and inductive molecules to repair or replace injured or diseased tissues and organs. Tremendous progress in biological and biomaterial aspects of this field have been accomplished to date, and several engineered tissues are now being used clinically. However, tissue engineers face major challenges in repairing or repl- ing tissues that serve a predominantly biomechanical function. To meet this challenge, the United States National Committee on Biomech- ics in 1998 adopted a new paradigm termed functional tissue engineering (FTE) to emphasize the importance of biomechanical considerations in the design and - velopment of cell and matrix-based implants for soft and hard tissue repair. Functional tissue engineering represents a relevant and exciting new discipline in the field of tissue engineering. Since many tissues, such as those of the muscu- skeletal, cardiovascular, and dental systems, are accustomed to being mecha- cally challenged, tissue-engineered constructs used to replace these tissues after injury or disease must certainly do the same. Of course, tissue engineers must also attempt to return normal biological activity in order for the construct to truly - tegrate with the surrounding tissues. Thus, the term functional can have many meanings, such as restoration of metabolic function. The primary focus of this text is on the role of biomechanical function in tissue engineering.
Additional text
From the reviews:
"Functional Tissue Engineering is a useful compilation of research by contributors involved in developing tissues … . It is not easy to extract a decent book from a conference, but the editors have done a very good job … . it will be an invaluable source for those starting a PhD … . I recommend it to those embarking on or already involved in engineering structural tissues. … The chapters are well written … . The book is clearly focused to encompass practical issues, such as the need to create appropriate biomechanical environments … ." (Sheila MacNeil, Materials Today, July/August, 2005)
Report
From the reviews:
"Functional Tissue Engineering is a useful compilation of research by contributors involved in developing tissues . It is not easy to extract a decent book from a conference, but the editors have done a very good job . it will be an invaluable source for those starting a PhD . I recommend it to those embarking on or already involved in engineering structural tissues. The chapters are well written . The book is clearly focused to encompass practical issues, such as the need to create appropriate biomechanical environments ." (Sheila MacNeil, Materials Today, July/August, 2005)
