Cell Survival and Cell Death, Second Edition

Written and edited by experts in the field, this collection provides a comprehensive update on the cell signaling that underlies the main cell death programs (apoptosis, pyroptosis, and necroptosis) and how this knowledge is driving the development of therapeutic drugs to treat some human diseases. Contributors describe in detail the molecular mechanisms of cell death signaling and the myriad players involved, including death receptor-ligand systems, BCL-2 family proteins, caspases, inflammasomes, gasdermin, MLKL, RIPK1, A20, and XIAP.

Product details

• Authors: Edward Miao, James Murphy, Kim Newton
• Assisted by: Edward Miao (Editor), Edward (University of North Carolina at Chapel Hill) Miao (Editor), James Murphy (Editor), James (Walter and Eliza Hall Institute of Medical Research) Murphy (Editor), Kim Newton (Editor), Kim (Genentech) Newton (Editor)
• Publisher: Cold Spring Harbor Laboratory Press
• Languages: English
• Product format: Hardback
• Released: 31.05.2020
• EAN: 9781621823551
• ISBN: 978-1-62182-355-1
• No. of pages: 310
• Dimensions: 183 mm x 259 mm x 20 mm
• Weight: 885 g
• Series: Perspectives Cshl
• Subjects: Natural sciences, medicine, IT, technology > Biology > Biochemistry, biophysics; Zellbiologie (Zytologie), Science, Entwicklungsbiologie, SCIENCE / Life Sciences / Developmental Biology, SCIENCE / Life Sciences / Biochemistry, SCIENCE / Life Sciences / Cell Biology