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This comprehensive text covers the research and development trends in the growing field of aromatic C-H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, copper-, cobalt-, ruthenium-, and ferric-catalyzed aromatic C(sp2)-H dehydrogenative cross-coupling reactions are described in detail. A useful reference source for researchers and graduates in the field of heterocyclic chemistry and transition-metal-catalyzed dehydrogenative coupling reactions.
Features:
Comprehensive volume on the synthesis of benzo-heterocycles via aromatic C(sp2)-H bond activation.
Heterocycles are of paramount importance to medicinal chemistry and drug discovery.
Provides a comprehensive literature survey on the construction of heterocycles.
Reaction procedures and mechanistic explanations are included, which will appeal to those in fine chemicals and pharmaceutical companies.
List of contents
Five-Membered N-Heterocycles; Six- and Higher-Membered N-Heterocycles; N-Bridged Heterocycles; e-Membered O-heterocycles; Six-, and Higher-Membered O-heterocycles; N,O-Heterocycles; N,S-Heterocycles; S-Heterocycles; Si-Heterocycles; P-Heterocycles; Alkaloids and Natural Products
About the author
Prof. Bagher Eftekhari-Sis obtained his PhD from Sharif University of Technology under the supervision of Prof. Mohammed M. Hashemi in 2009 and then joined the Chemistry Department of the University of Maragheh. His research field involves the synthesis of heterocyclic compounds, supported catalysts, and polymeric and nano-materials. He has some reviews in the fields of organic transformations, especially in the heterocycle synthesis trends in the leading chemistry journal Chemical Reviews.
Summary
A unique volume covering all types of heterocycles synthesized via aromatic C-H dehydrogenative coupling reactions. The book will appeal to research groups around the world working on organic synthesis, heterocyclic compounds, catalysts, and medicinal chemistry.
