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The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide a synopsis of novel mechanisms by which HSP70 is involved in the regulation of human diseases and disorders. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for medical students and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology.
List of contents
Heat Shock Protein 70 and Molecular Confession during Neurodegeneration.- Hsp70-Family Proteins and Neurodegenerative Diseases.- Heat Shock Protein70 in Neurological Disease.- Involvement of Heat Shock Protein 70 (Hsp70) in Gastrointestinal Cancers.- Heat Shock Protein 70 and Cancer.- Implication of HSP70 in the Pathogenesis of Gastric Cancer.- Double Face of eHsp70 in Front of Different Situations.- HSP70 is a Major Contributor to the MHCII Ligandome and Inducer of Regulatory T Cells.- Immune Properties of HSP70.- Molecular Chaperones Regulating the Dynamics, Composition and Functionality of RNP Granules: Implications for Age-related Diseases.- Heat Shock Proteins in Cardiovascular Diseases: From Bench to Bedside.- Clinical Implication of Heat Shock Protein 70 in Kidney Disease.- Heat Shock Proteins in the Kidney - What is Known About their Role in Kidney Disease.- Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina.- Emerging Role of HSP70 in Human Diseases.- Intranasal Administration of Hsp70: Molecular and Therapeutic Consequences.- The Effectiveness of Antitumor Vaccine Enriched with a Heat Shock Protein 70.- Mammalian Heat Shock Protein Hsp105: The Hsp70 Inducer and a Potent Target for Cancer Therapy.- Suppression of HSP70 Expression by Quercetin and its Therapeutic Potential against Cancer.- Hsp70 in Fungi: Evolution, Function and Vaccine Candidate.
Summary
The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide a synopsis of novel mechanisms by which HSP70 is involved in the regulation of human diseases and disorders. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for medical students and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology.
