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This book presents the latest knowledge on all aspects of severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease endemic to China, South Korea, and Japan that is caused by a bunyavirus first discovered in 2011, widely referred to as SFTS virus (SFTSV) though recently renamed Huaiyangshan banyangvirus. The contents will be of interest for the light that they cast on not only this viral infection but viral hemorrhagic fevers in general. The opening chapters summarize general considerations and perspectives regarding SFTS and describe the discovery process in each of the affected countries. The basic mechanism of SFTSV infection is then examined from the perspectives of epidemiology, pathology, and virology. The book goes on to examine in detail the mode of spread and transmission of SFTSV, means of infection control, and diagnosis and therapy. The final two chapters explore Heartland virus infections and Crimean-Congohemorrhagic fever with the aim of highlighting similarities and differences compared with SFTS. This book will be of interest to all researchers who study emerging viruses and infections, whether in Asia or elsewhere, as well as to clinicians who may encounter SFTS.
List of contents
1. Introduction.- 2. The Discovery Process of SFTS in China.- 3. The discovery process of SFTS in Japan.- 4. Severe Fever with Thrombocytopenia Syndrome in the Republic of Korea.- 5. Virology of SFTSV.- 6. Molecular epidemiology of SFTSV.- 7. Epidemiology of SFTS in China.- 8. Epidemiology of SFTS virus from ticks and animals in the Republic of Korea.- 9. Epidemiology of SFTS in Japan.- 10. Seroprevalence and risk factors of severe fever with thrombocytopenia syndrome : Seroepidemiology of SFTS.- 11. Clinical aspects of SFTS.- 12. Pathology of severe fever with thrombocytopenia syndrome.- 13. Circulation of severe fever with thrombocytopenia syndrome virus (SFTSV) in nature: transmission of SFTSV between mammals and ticks.- 14. Laboratory diagnosis for SFTS.- 15. Antiviral drugs for the therapeutics of SFTS.- 16. Infection control and prevention in hospitals and household.- 17. Animal experimental models for the study on severe fever with thrombocytopenia syndrome virus infection.- 18. Similarity and difference in characteristics of two diseases, SFTS and CCHF, and their causative agents.
About the author
Editor:
Dr. Masayuki Saijo, Director of the Department of Virology 1, National Institute of Infectious Disease, Tokyo, Japan
Summary
This book presents the latest knowledge on all aspects of severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease endemic to China, South Korea, and Japan that is caused by a bunyavirus first discovered in 2011, widely referred to as SFTS virus (SFTSV) though recently renamed Huaiyangshan banyangvirus. The contents will be of interest for the light that they cast on not only this viral infection but viral hemorrhagic fevers in general. The opening chapters summarize general considerations and perspectives regarding SFTS and describe the discovery process in each of the affected countries. The basic mechanism of SFTSV infection is then examined from the perspectives of epidemiology, pathology, and virology. The book goes on to examine in detail the mode of spread and transmission of SFTSV, means of infection control, and diagnosis and therapy. The final two chapters explore Heartland virus infections and Crimean-Congohemorrhagic fever with the aim of highlighting similarities and differences compared with SFTS. This book will be of interest to all researchers who study emerging viruses and infections, whether in Asia or elsewhere, as well as to clinicians who may encounter SFTS.
