Fr. 106.00

Clinical Laboratory Animal Medicine - An Introduction

English · Paperback / Softback

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Description

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The revised fifth edition of Clinical Laboratory Animal Medicine: An Introduction is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals.
 
The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and genetic editing, and expanded coverage of environmental enrichment and pain management. The book presents helpful tip boxes, images, and review questions to aid in comprehension and learning, and a companion website provides editable review questions and answers, instructional PowerPoints, and additional images not found in the book. This important text:
 
* Provides a complete introduction to laboratory animal husbandry, diseases, and treatments
* Offers a user-friendly format with helpful content that highlights important concepts
* Contains new knowledge relating to technical methodologies, diseases, drug dosages, laws and regulations, and organizations
* Covers information on regulations, facilities, equipment, housing, and research variables as well as veterinary care
* Includes new chapters on zebrafish and cattle, sheep, goats, and pigs
 
Written for veterinary technicians, veterinary students, practicing veterinarians, and research scientists, the fifth edition of Clinical Laboratory Animal Medicine continues to offer an essential guide to the ethical treatment and anatomic and physiological characteristics of research animals.

List of contents

About the Authors xii
 
Preface xiii
 
About the Companion Website xiv
 
1 Introduction to Laboratory Animal Medicine 1
 
Animals Used in Research, Teaching, and Testing 2
 
Ethical Considerations 8
 
Organizations 12
 
Bibliography 17
 
Further Reading 18
 
Chapter 1 Review 19
 
2 Regulations, Policies, and Principles Governing the Care and Use of Laboratory Animals 22
 
Animal Welfare Act and Regulations 22
 
Public Health Service Policy on Humane Care and Use of Laboratory Animals 28
 
Other Regulations, Policies, Guidance Documents, and Organizations 31
 
References 36
 
Further Reading 37
 
Chapter 2 Review 37
 
3 Facility Design, Housing, Equipment, and Management 39
 
Laboratory Animal Facility Design 39
 
Common Facility Classifications 46
 
Housing 50
 
Facility Equipment 59
 
Management 66
 
Bibliography 69
 
Further Reading 69
 
Chapter 3 Review 71
 
4 Mice 74
 
Genetics 74
 
Microbiologic Classifications 76
 
Uses 77
 
Behavior 77
 
Anatomic and Physiologic Features 78
 
Breeding and Reproduction 80
 
Husbandry 81
 
Techniques 86
 
Special Techniques: Transgenic Production Technology 96
 
Therapeutic Agents 101
 
Introduction to Diseases of Mice 101
 
Viral Diseases 107
 
References 114
 
Further Reading 119
 
Chapter 4 Review 122
 
5 Rats 124
 
Genetics 124
 
Microbiologic Classifications 125
 
Uses 126
 
Behavior 126
 
Anatomic and Physiologic Features 127
 
Breeding and Reproduction 129
 
Husbandry 130
 
Techniques 133
 
Therapeutic Agents 143
 
Introduction to Diseases of Rats 144
 
Bibliography 157
 
Further Reading 162
 
Chapter 5 Review 162
 
6 Gerbils 165
 
Uses 165
 
Behavior 166
 
Anatomic and Physiologic Features 166
 
Breeding and Reproduction 167
 
Husbandry 168
 
Techniques 170
 
Therapeutic Agents 176
 
Introduction to Diseases of Gerbils 176
 
Bibliography 181
 
Further Reading 183
 
Chapter 6 Review 184
 
7 Hamsters 185
 
Uses 185
 
Behavior 186
 
Anatomic and Physiologic Features 187
 
Breeding and Reproduction 189
 
Husbandry 190
 
Techniques 192
 
Therapeutic Agents 198
 
Introduction to Diseases of Hamsters 198
 
Bibliography 207
 
Further Reading 209
 
Chapter 7 Review 210
 
8 Guinea Pigs 212
 
Uses 212
 
Behavior 213
 
Anatomic and Physiologic Features 214
 
Breeding and Reproduction 216
 
Husbandry 218
 
Techniques 219
 
Therapeutic Agents 225
 
Introduction to Diseases of Guinea Pigs 226
 
Bibliography 238
 
Further Reading 240
 
Chapter 8 Review 242
 
9 Chinchillas 243
 
Uses 243
 
Behavior 244
 
Anatomic and Physiologic Features 244
 
Breeding and Reproduction 246
 
Husbandry 247
 
Techniques 249
 
Therapeutic Agents 253
 
Introduction to Diseases of Chinchillas 255
 
Bibliography 260
 
Further Reading 262
 
Chapter 9 Review 262
 
10 Zebrafish 264
 
Uses 264
 
Behavior 265
 
Anatomic and Physiologic Features 265
 
Reproduct

About the author

The authors

Lesley A. Colby, DVM, MS, DACLAM, is an Associate Professor and Senior Director of Animal Resources and Operations in the Department of Comparative Medicine at the University of Washington in Seattle, Washington, USA.

Megan H. Nowland, DVM, DACLAM, is an Associate Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA.

Lucy H. Kennedy, DVM, DACLAM, is an Assistant Professor in the Unit for Laboratory Animal Medicine at the University of Michigan in Ann Arbor, Michigan, USA.

Summary

The revised fifth edition of Clinical Laboratory Animal Medicine: An Introduction is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals.

The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and genetic editing, and expanded coverage of environmental enrichment and pain management. The book presents helpful tip boxes, images, and review questions to aid in comprehension and learning, and a companion website provides editable review questions and answers, instructional PowerPoints, and additional images not found in the book. This important text:

* Provides a complete introduction to laboratory animal husbandry, diseases, and treatments
* Offers a user-friendly format with helpful content that highlights important concepts
* Contains new knowledge relating to technical methodologies, diseases, drug dosages, laws and regulations, and organizations
* Covers information on regulations, facilities, equipment, housing, and research variables as well as veterinary care
* Includes new chapters on zebrafish and cattle, sheep, goats, and pigs

Written for veterinary technicians, veterinary students, practicing veterinarians, and research scientists, the fifth edition of Clinical Laboratory Animal Medicine continues to offer an essential guide to the ethical treatment and anatomic and physiological characteristics of research animals.

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