Hormones, Metabolism and the Benefits of Exercise

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel "myokines" that might act as new therapeutic agents in the future.

List of contents

Introduction.- Human brown adipose tissue plasticity: hormonal and environmental manipulation.- The energy sensor AMPK: Adaptations to exercise, nutritional and hormonal signals.- Plasma steroids and cardiorespiratory fitness response to regular exercise.- Sending the signal: Muscle glycogen availability as a regulator of training adaptation.- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle.- Skeletal muscle microRNAs: Roles in differentiation, disease and exercise.- Tryptophan-kynurenine metabolites in exercise and mental health.- FNDC5/irisin - their role in the nervous system and as a mediator for beneficial effects of exercise on the brain.

About the author

Bruce Spiegelman is a Professor of Cancer Biology at Harvard Medical School and a Stanley J. Korsmeyer Professor of Cell Biology and Medicine

Summary

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Product details

• Assisted by: Bruc Spiegelman (Editor), Bruce Spiegelman (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 01.01.2018
• EAN: 9783030102685
• ISBN: 978-3-0-3010268-5
• No. of pages: 102
• Dimensions: 155 mm x 6 mm x 235 mm
• Weight: 186 g
• Illustrations: X, 102 p.
• Series: Research and Perspectives in Endocrine Interactions
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; Diabetes, Endokrinologie, B, Krankheiten und Störungen, Public Health und Präventivmedizin, Kardiologie, Angiologie, Diseases, Cardiology, METABOLISM, INTERNAL MEDICINE, Endocrinology, molecular biology, health promotion, Public health & preventive medicine, Biomedical and Life Sciences, Biomedical Research, Health Promotion and Disease Prevention, Molecular Medicine, Cardiovascular medicine, Metabolic Diseases