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This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field.
Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.
List of contents
PMCA.- Calcium channel.- Sodium/calcium exchanger.- Endoplasmic Reticulum.- SERCA Pump H.- IP3R.- IP3R.- RyR.- History of the SOCE concept.- STIM/Orai.- TRPC channel.- MCU complex.- VDAC.- Annexins.- Cytokinesis and Ca2+ signaling.
About the author
Prof. Joachim Krebs is Prof. Emeritus of the Swiss federal Institute of Technology (ETH) ; at present he is Consultant at the MPI for Biophysical Chemistry, Department on NMR-based Structural Biology, Göttingen, Germany. Prof. Krebs was working for more than 30 years in the field of calcium signaling, calcium-binding and calcium-transport proteins and has importantly contributed to the understanding of calcium function and signaling pathways in the cell.
Summary
This book describes the newest discoveries on calcium signaling happening at the cellular and intracellular membranes, often exerted in so called microdomains. Calcium entry and release, its interaction with proteins and resulting events on proteins and organelles are comprehensively depicted by leading experts in the field.
Knowledge about details of these highly dynamic processes rapidly increased in recent years, the book therefore provides a timely summary on the processes of calcium signaling and related membrane dynamics; it is aimed at students and researchers in biochemistry and cell biology.
