Leukemia and Lymphoma: Molecular and Therapeutic Insights

Written and edited by experts in the field, this collection covers our current understanding of the molecular underpinnings of leukemia and lymphoma, as well as recent progress in development of therapies that target them. The contributors review the normal functions of hematopoietic stem cells--the precursors to white blood cells--and then examine the genetic, epigenetic, and cellular mechanisms that drive malignant transformation. The roles of clonal hematopoiesis, RNA-binding proteins, and alterations in metabolism and cell signaling (e.g., MAP kinase pathways) are among the topics covered in depth, along with the parts they play in specific types of leukemia and lymphoma.

Product details

• Authors: Michael G Kharas, Michael G. Kharas, Ross L Levine, Ari M Melnick
• Assisted by: Michael Kharas (Editor), Michael G Kharas (Editor), Michael G (Center for Experimental Therapeutics Sloan Kettering Institute) Kharas (Editor), Michael G. Kharas (Editor), Ross L Levine (Editor), Ross L (Memorial Sloan Kettering Cancer Center) Levine (Editor), Ross L. Levine (Editor), Ari M Melnick (Editor), Ari M (Weill Cornell Medical College Cornell University) Melnick (Editor), Ari M. Melnick (Editor)
• Publisher: Cold Spring Harbor Laboratory Press
• Languages: English
• Product format: Hardback
• Released: 30.09.2020
• EAN: 9781621821427
• ISBN: 978-1-62182-142-7
• No. of pages: 520
• Dimensions: 185 mm x 259 mm x 30 mm
• Weight: 1474 g
• Series: Perspectives Cshl
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; Immunologie, MEDICAL / Diseases, MEDICAL / Immunology, MEDICAL / Oncology, Medical / Nursing