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This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers' understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future.Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also beof interest to the parents of pediatric patients, and to co-medical staffs.
List of contents
Part I: Hematopoiesis.- Hematopoietic Stem Cells.- Part II: White Blood Cell Disorders.- Acute Lymphoblastic Leukemia.- Acute Myeloid Leukemia.- Myelodysplastic syndrome and JMML.- Leukopenia (neutropenia).- Part III: Red Blood Cell Disorders.- Aplastic Anemia.- Bone marrow failure, TAM.- Part IV: Platelet and Coagulation Disorders.- Immune and inherited thrombocytopenia.- Hemophilia.- Thrombosis.- Part V: Histiocytic Disorders.- Langerhans Cell Histiocytosis.- Hemophagocytic Lymphohistiocytosis, primary.- Hemophagocytic Lymphohistiocytosis, secondary.
About the author
Editor: Dr Eiichi Ishii, Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Japan
Summary
This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future.
Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also beof interest to the parents of pediatric patients, and to co-medical staffs.
Additional text
“This unique treatise describes the pathogenesis and treatment modalities of childhood hematologic disorders that are both currently in use and that show future promise. ... The intended audience includes not only medical specialists who are involved in treating pediatric patients, but also medical students, research scientists, and even parents of afflicted children who can gain some perspective on the complexities of these disorders and the progress being made to treat them.” (Ravi Salgia, Doody's Book Reviews, April, 2018)
“A concise treatise which in 3 chapters divided into 3 parts summarizes present knowledge on hematological diseases in childhood. With illustrations, tables and many references. For pediatricians in practice and in training.” (Pediatric Endocrinology Reviews, Vol. 15 (2), December, 2017)
Report
"This unique treatise describes the pathogenesis and treatment modalities of childhood hematologic disorders that are both currently in use and that show future promise. ... The intended audience includes not only medical specialists who are involved in treating pediatric patients, but also medical students, research scientists, and even parents of afflicted children who can gain some perspective on the complexities of these disorders and the progress being made to treat them." (Ravi Salgia, Doody's Book Reviews, April, 2018)
"A concise treatise which in 3 chapters divided into 3 parts summarizes present knowledge on hematological diseases in childhood. With illustrations, tables and many references. For pediatricians in practice and in training." (Pediatric Endocrinology Reviews, Vol. 15 (2), December, 2017)
