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The intimate relationship between form and function inherent in the design of animals is perhaps nowhere more evident than in the musculoskeletal system. This book, about how function determines form, addresses the role of mechanical factors in the development, adaptation, maintenance, aging, and repair of skeletal tissues. The authors refer to this process as mechanobiology and develop their theme within an evolutionary framework. They show how degenerative disorders such as arthritis and osteoporosis are regulated by the same mechanical processes that influence normal development and growth. Skeletal Function and Form bridges important gaps among disciplines, providing a common ground for a multidisciplinary understanding.
List of contents
Preface; 1. Form and function; 2. Skeletal tissue histomorphology and mechanics; 3. Cartilage differentiation and growth; 4. Perichondral and periosteal ossification; 5. Endochondral growth and ossification; 6. Cancellous bone; 7. Skeletal tissue regeneration; 8. Articular cartilage development and destruction; 9. Mechanobiology in skeletal evolution; 10. The physical nature of living things; Appendix A. Material characteristics; Appendix B. Structural characteristics; Appendix C. Failure characteristics; Index.
Summary
This book addresses the role of mechanical factors in the development, adaptation, maintenance, ageing, and repair of skeletal tissues such as bones, cartilage, tendons, ligaments and muscles. The authors show how the normal development of skeletal tissues is influenced by mechanical stimulation beginning in the embryo and continuing throughout life into old age.
