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List of contents
Biographies vii
Preface ix
About the Companion Website xi
1 Basic Statistical Background 1 1.1 Introduction 1
2 The Screening Phase 23 2.1 Introduction 23
2.2 Case Study: Air Freshener Project 24
2.2.1 Plan of the Screening Experiment 24
2.2.2 Plan of the Statistical Analyses 37
3 Product Development and Optimization 57 3.1 Introduction 57
3.2 Case Study for Single Sample Experiments: Throat Care Project 59
3.2.1 Comparing the Mean to a Specified Value 60
3.2.2 Comparing a Proportion to a Specified Value 67
3.3 Case Study for TwöSample Experiments: Condom Project 73
3.3.1 Comparing Variability Between Two Groups 74
3.3.2 Comparing Means Between Two Groups 81
3.3.3 Comparing Two Proportions 85
3.4 Case Study for Paired Data: Fragrance Project 93
3.5 Case Study: Stain Removal Project 104
3.5.1 Plan of the General Factorial Experiment 104
3.5.2 Plan of the Statistical Analyses 110
4 Other Topics in Product Development and Optimization: Response Surface and Mixture Designs 137 4.1 Introduction 137
4.2 Case Study for Response Surface Designs: Polymer Project 138
4.2.1 Plan of the Experimental Design 139
4.2.2 Plan of the Statistical Analyses 150
4.3 Case Study for Mixture Designs: Mix¿Up Project 166
4.3.1 Plan of the Experimental Design 167
4.3.2 Plan of the Statistical Analyses 199
5 Product Validation 213 5.1 Introduction 213
5.2 Case Study: GERD Project 215
5.2.1 Evaluation of the Relationship among Quantitative Variables 215
5.3 Case Study: Shelf Life Project (Fixed Batch Factor) 243
5.4 Case Study: Shelf Life Project (Random Batch Factor) 250
6 Consumer Voice 257 6.1 Introduction 257
6.2 Case Study: "Top¿Two Box" Project 259
6.3 Case Study: DOE - Top Score Project 284
6.3.1 Plan of the Factorial Design 284
6.3.2 Plan of the Statistical Analyses 285
6.4 Final Remarks 291
References 293
Index 295
About the author
ROSA ARBORETTI is Associate Professor of Statistics at the Department of Civil, Environmental and Architectural Engineering at the University of Padova, Italy.
MATTIA DE DOMINICIS is a former R&D Vice-President in Household and Personal Care at Reckitt Benckiser in Venice, Italy.
CHRIS JONES is Vice President of R&D in Hygiene Home at Reckitt Benckiser in Montvale, USA.
LUIGI SALMASO is Full Professor of Statistics and Deputy Chair of the Department of Management and Engineering at the University of Padova, Italy.
