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This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiactransplant recipients. Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.
List of contents
Autonomic Innervation System in the Heart: Anatomy and Molecular Biology.- Neural Control of Cardiac Function in Health and Disease.- Chemistry and Biology of Radiotracers Designed to Target Changes in the Myocardial Sympathetic and Parasympathetic Nervous Systems as a Function of Disease or Treatment.- Neuronal Imaging in Heart Failure.- PET Imaging and Quantitation of Cardiac Innervation.- Neuronal Imaging and Reverse Remodeling.- Neuronal Imaging, Ventricular Arrhythmias, and Device Therapy in Heart Failure.- Cardiac Sympathetic Innervation and Ablation of Ventricular Tachycardia.- Dysautonomia: From the Brain Disorders to Neuropathies (including Diabetes).- Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow.
About the author
Vasken Dilsizian, MD, University of Maryland School of Medicine, Baltimore, MD, USA
Jagat Narula, MD, PhD, Mount Sinai Medical Center, New York, NY, USA
Drs. Dilsizian and Narula are the editors of Atlas of Nuclear Cardiology, 4th ed (2013)
Summary
This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiactransplant recipients. Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.
