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This textbook discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of (1) experimental procedures and (2) interpreting data.
List of contents
Introduction.- Antibiotic resistance development.- Major classes of antibiotics.- Relevant concepts in Biochemistry.- The cell wall as a target.- Mechanism of resistance to B-lactams.- Antibiotic Vancomycin.- Antibiotics that inhibit nucleotide synthesis.- Antibiotics that inhibit DNA synthesis.- Drugs that cause DNA cleavage.- Antibiotics that inhibit RNA synthesis.- Antibiotics that inhibit RNA synthesis.- Antibiotics that disrupt membrane structure.
About the author
Mrinal Bhattacharjee is an Associate Professor at Long Island University.
Summary
This textbook discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of (1) experimental procedures and (2) interpreting data.
Additional text
“In the Chemistry of Antibiotics and Related Drugs, Bhattacharjee (chemistry and biochemistry, Long Island Univ.) writes about the many different classes of compounds approved over the last century that still are, or have been, used to treat infectious diseases. The book is organized around the targets of these compounds. … this book is heavily referenced and will be valuable to practicing researchers and advanced students. Summing Up: Recommended. Upper-division undergraduates and above; faculty and professionals.” (P. W. Baures, Choice, Vol. 54 (9), May, 2017)
Report
"In the Chemistry of Antibiotics and Related Drugs, Bhattacharjee (chemistry and biochemistry, Long Island Univ.) writes about the many different classes of compounds approved over the last century that still are, or have been, used to treat infectious diseases. The book is organized around the targets of these compounds. ... this book is heavily referenced and will be valuable to practicing researchers and advanced students. Summing Up: Recommended. Upper-division undergraduates and above; faculty and professionals." (P. W. Baures, Choice, Vol. 54 (9), May, 2017)
