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This book is a rich source of information on point-of-care (POC) tests for the diagnosis and treatment of severe hemorrhage, including thromboelastography, thromboelastometry, heparin monitoring systems, and platelet function analyzers (Multiplate, PFA-100, VerifyNow, etc.). The opening chapters focus on the pathophysiology of coagulation and the general characteristics of POC devices. The relevance of POC tests in specific scenarios is then carefully explained, with guidance on their use in contexts including trauma, cardiovascular surgery, ECMO, liver surgery, postpartum hemorrhage, and disorders of hemostasis in the critically ill. An individual chapter is devoted to practical issues when applying POC tests, and the book closes by presenting a set of informative clinical cases. As POC devices gain increasing popularity as bedside diagnostic tools in different clinical settings, it is important for practitioners to understand their role and value. Point-of-Care Tests for Severe Hemorrhage will be a useful and reliable source of information for anesthesiologists, intensivists, cardiologists, and hematologists.
List of contents
Pathophysiology of coagulation.- General aspects of viscoelastic tests.- General aspects of platelet function tests.- Other POC tests.- POC tests in clinical practice: history.- Blood derivates and prohemostatic drugs.- Clinical management of severe bleeding in trauma patients.- Clinical management of severe bleeding in cardiovascular patients.- Clinical management of post-partum hemorrhage.- Clinical management of severe bleeding in liver surgery.- Disorders of hemostasis in critically ill patients.- Assessment of the effects of antithrombotic drugs.- Practical issues in POC tests.- Clinical cases.
Report
"Reading this manual for the diagnosis and treatment of coagulopathy is highly recommended for both beginners learning to use point-of-care testing (POCT) for coagulation monitoring and experienced users. It is comprised of thorough basic information including how to do the tests, how they work, and how to interpret test results as well as the descriptions of new developments and prototype devices that serve as food for thought regarding strategic evolvement and future clinical trials." (Sibylle Kozek-Langenecker, Anesthesia & Analgesia, Vol. 124 (1), January, 2017)
"This is a collection of reviews that describe bedside testing modalities enabling dissection of the etiology of hemorrhage in a variety of clinical settings. ... Any clinician managing the bleeding patient, including intensivists, traumatologists, anesthesiologists, obstetricians, and hematologists, may benefit from this book. ... This is an excellent summary of the physiological basis and potential application of a collection of technologies that are receiving significant attention in the management of the bleeding patient." (David J. Dries, Doody's Book Reviews, March, 2016)
"The first edition of this manual successfully achieved the objectives of the authors in compiling current, comprehensive, and relevant information on POCTs and their application in various severe hemorrhage scenarios. This textbook will appeal to a broad readership of trainees and clinicians of different disciplines involved in the management of this challenging group of patients." (Carlos Corredor, Canadian Journal of Anesthesia, Vol. 63, 2016)
