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This new, revised and updated edition takes into account the most recent advances in the understanding of human pathophysiology. The book presents the complex basic principles of vascular hemodynamics and its pathophysiologie in a direct and effective way, stressing the importance of the mechanical properties of large arteries in the origin of blood pressure. The readily understandable text, supported by helpful images, describes the elements that define blood pressure and explains such important concepts as pulse wave velocity, central blood pressure, reflected waves, and pulse pressure amplification. Entirely new chapters are included on the sympathetic nervous system and arterial stiffness and on the role played by arterial stiffness in influencing blood pressure variability. The book will enable the physician to answer some of the key questions encountered when addressing the problem of arterial hypertension in everyday clinical practice: How is blood pressure generated? How shouldblood pressure values be interpreted? Is systolic blood pressure of greater importance than diastolic blood pressure?
List of contents
1 Blood Pressure and Vascular Hemodynamics.- 2 Pulse Wave Velocity and Arterial Stiffness Assessment.- 3 Arterial Stiffness and Blood Pressure Variability.- 4 Central Blood Pressure: Part 1, pathophysiology.- 5 Central Blood Pressure: Part 2, Pulse Wave Analysis.- 6 Aortic Stiffness and Myocardial Ischemia.- 7 Arterial Stiffness in Chronic Kidney Disease.- 8 Pulse Wave Velocity and Pulse Wave Analysis in Experimental Animals.
About the author
Paolo Salvi, MD, PhD, is a specialist in Internal Medicine and Cardiology. He was Associate Professor in Internal Medicine, Geriatrics and Biology of Aging at Henri Poincaré University of Nancy (France) from 2007 to 2010. At present he is a researcher at the Istituto Auxologico Italiano in Milan, and adjunct professor in Cardiology at University of Milano-Bicocca, Milan (Italy).
Summary
This new, revised and updated edition takes into account the most recent advances in the understanding of human pathophysiology. The book presents the complex basic principles of vascular hemodynamics and its pathophysiologie in a direct and effective way, stressing the importance of the mechanical properties of large arteries in the origin of blood pressure. The readily understandable text, supported by helpful images, describes the elements that define blood pressure and explains such important concepts as pulse wave velocity, central blood pressure, reflected waves, and pulse pressure amplification. Entirely new chapters are included on the sympathetic nervous system and arterial stiffness and on the role played by arterial stiffness in influencing blood pressure variability. The book will enable the physician to answer some of the key questions encountered when addressing the problem of arterial hypertension in everyday clinical practice: How is blood pressure generated? How shouldblood pressure values be interpreted? Is systolic blood pressure of greater importance than diastolic blood pressure?
