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Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy.
List of contents
Chapter 1: Image-Guided Focused Ultrasound Therapy: Past, Current and Future. Chapter 2: Physical Principles of Focused Ultrasound Therapy. Chapter 3: Mechanisms for Induction of Bio-Effects of Focused Ultrasound in Tissue. Chapter 4: Image-Guided Focused Ultrasound Therapy: Physics and Clinical Applications. Chapter 5: Calibration and quality assurance for high intensity focused ultrasound fields. Chapter 6: Numerical Modelling for Simulation and Planning of Focused Ultrasound Treatments. Chapter 7: Ultrasound Monitoring Techniques for Focused Ultrasound Therapy. Chapter 8: Extracorporeal Ultrasound-guided HIFU Devices -- Clinical Application, Treatment Planning and B-mode Ultrasound for Real-time Monitoring and Controlling of Treatment. Chapter 9: Imaging Assessments of Tumour Response and Treatment Outcome after High-intensity Focused Ultrasound Ablation. Chapter 10: Focused Ultrasound Treatment of the Prostate: Devices and Clinical Results. Chapter 11: Ultrasound-Guided Focused Ultrasound Ablation for Uterine Fibroids. Chapter 12: Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Liver Tumours. Chapter 13: Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Kidney Tumours. Chapter 14: Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Pancreatic Cancer. Chapter 15: Clinical Application of Ultrasound-Guided Focused Ultrasound Ablation for Breast Tumours. Chapter 16: Clinical Application of Ultrasound-guided High Intensity Focused Ultrasound Treatment for Primary Bone Malignancies and Soft Tissue Sarcomas. Chapter 17: Clinical Extracorporeal MR-Guided Focused Ultrasound Systems: Treatment Planning, Therapy Delivery, and Online Monitoring via Thermometry and Thermal Dose Mapping. Chapter 18: Clinical Application of MR-Guided Focused Ultrasound Ablation for Uterine Fibroids. Chapter 19: Clinical Application of MR-Guided Focused Ultrasound Ablation for Tumours in the Breast. Chapter 20: Clinical Application of MR-Guided Focused Ultrasound Ablation for Bone Metastasis. Chapter 21: Clinical Application of MR-Guided Focused Ultrasound Therapy in the Brain. Chapter 22: Sonoporation: Concept, Mechanisms and Application to Cancer Treatment. Chapter 23: Nano/Microbubble-assisted Ultrasound for Drug Delivery in Cancer. Chapter 24: Anaesthesia, Ventilation and immobilisation Strategies for Focused Ultrasound Therapy (with special reference to high frequency ventilation). Chapter 25: Triggered Temperature-Sensitive Liposome Rlease by Focused Ultrasound for Localised Drug Delivery. Chapter 26: Transcranial Ultrasound-Mediated Blood-Brain Barrier Disruption for Targeted Drug Delivery. Chapter 27: Histotripsy: Focused Ultrasound Therapy by Mechanical Tissue Fractionation. Chapter 28: Focused Ultrasound Ablation Enhancement of Specific Antitumour Immunity. Chapter 29: Focused Ultrasound Therapy for Treatment of Pain.
About the author
Professor Gail ter Haar, DSc, is a renowned expert who works at the intersection of focused ultrasound and physics and leads the therapeutic ultrasound team at The Institute for Cancer Research (ICR), UK. Gail is founding President of the International Society for Therapeutic Ultrasound (ISTU).
Dr. Ian Rivens, PhD, is a Staff Scientist at The Institute for Cancer Research (ICR), UK with a background in biomedical physics and 35 experience of developing equipment and techniques in the laboratory and translating them to bed-side research via clinical trials in oncology and fetal medicine He is a founding member of ISTU with extensive experience of supervising PhD and MD students.
Professor Feng Wu, MD & PhD, is a world-leading HIFU surgeon who works in clinical applications of focused ultrasound therapy. Feng is currently working as HIFU Consultant at Oxford University Hospitals, and also serving as Senior Clinical Scientist at Nuffield Department of Surgical Sciences, University of Oxford, UK. He is a co-founder and the first Secretary of the International Society for Therapeutic Ultrasound (ISTU).
Summary
Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy.
