Foundations for High-Throughput Omics Data Analysis - Methods, Theories and Applications

The aim of this textbook is to train new researchers in analyzing high-throughput omics data by building fundamental skills instead of focusing on technology or platform-specific features that change every few years. The authors seek a balance between breadth and depth in the broad field. The book contains many real examples to illustrate the methodological concept and biological relevance. Computer lab materials (data and hands-on programming code) are included along with homework exercises to provide real-world data analysis experiences.

List of contents

High-Throughput Omics Data. Experimental Design and Data Preprocessing. Differential and Association Analysis. Dimension Reduction. Robust Nonparametric Methods. Unsupervised Machine Learning and Clustering. Supervised Machine Learning I: Methods. Supervised Machine Learning II: Concept and Principles. Regularization Method. Bayesian Methods and Applications. Network Analysis. Enrichment Analysis. Meta-Analysis and Integrative Analysis. Selected Computational Algorithms. Reproducible Research and Critical Thinking in Bioinformatics. Appendix: Case Studies.

About the author

George C. Tseng is an associate professor in the Department of Biostatistics at the University of Pittsburgh, Pennsylvania, USA

Zhiguang Huo and Tianzhu Ma are PhD students at the University of Pittsburgh, Pennsylvania, USA

Summary

The aim of this textbook is to train new researchers in analyzing high-throughput omics data by building fundamental skills instead of focusing on technology or platform-specific features that change every few years. The authors seek a balance between breadth and depth in the broad field. The book contains many real examples to illustrate the methodological concept and biological relevance. Computer lab materials (data and hands-on programming code) are included along with homework exercises to provide real-world data analysis experiences.

Product details

• Authors: Zhiguang Huo, Huo Zhiguang, Tianzhou Ma, Tianzhou (Department of Biostatistics Ma, Ma Tianzhou, George C. Tseng, George C. Huo Tseng, Tseng George C.
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Released: 19.08.2023
• EAN: 9781498706506
• ISBN: 978-1-4987-0650-6
• No. of pages: 400
• Series: Chapman & Hall/CRC Biostatistics Series; Chapman & Hall/CRC Biostatistics Series
• Subjects: Natural sciences, medicine, IT, technology > IT, data processing > General, dictionaries; Social sciences, law, business > Media, communication > Communication science; MATHEMATICS / Probability & Statistics / General, SCIENCE / Life Sciences / Biology, SCIENCE / Biotechnology, Biology, life sciences, Data analysis: general, Scientific research, Data capture and analysis, Data Capture & Analysis, Data science and analysis