Color Atlas of Clinical Hematology - Molecular and Cellular Basis of Disease

Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice
 
The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day.
 
Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems.
* Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images
* Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities
* Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format
* Includes and illustrates the WHO Classification of Hematologic Malignancies
* Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases
 
Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.

List of contents

Preface xxx
 
1 Molecular Biology of the Cell
 
2 Hematopoiesis
 
3 Growth Factor Signaling
 
4 Erythropoiesis and Examination of the Peripheral Blood and Bone Marrow
 
5 Hypochromic Anemias
 
6 The Porphyrias and Iron Overload
 
7 Megaloblastic Anemias
 
8 Hemolytic Anemias
 
9 Genetic Disorders of Hemoglobin
 
10 Benign Disorders of Phagocytes
 
11 Benign Disorders of Lymphocytes and Plasma Cells
 
12 Aplastic and Dyserythropoietic Anemias
 
13 The Hematologic Neoplasms: Laboratory Techniques and Acute Myeloid Leukemia
 
14 Acute Lymphoblastic Leukemia
 
15 Myelodysplastic Syndromes
 
16 Myeloproliferative Neoplasms
 
17 Mastocytosis, Myeloid/Lymphoid Neoplasms with Eosinophilia and Specific Cytogenetic Rearrangements, Myelodysplastic/Myeloproliferative Neoplasms
 
18 Chronic Lymphocytic Leukemia and Other Mature B- and T/Nk-Cell Leukemias
 
19 Small B-Cell Lymphomas
 
20 Aggressive Mature B-Cell Neoplasms
 
21 Myeloma and Related Neoplasms
 
22 Peripheral T- and NK-Cell Neoplasms
 
23 Hodgkin Lymphoma
 
24 Histiocytic Disorders
 
25 Stem Cell Transplantation
 
26 Normal Hemostasis, Platelet Production and Function
 
27 Vascular and Platelet Bleeding Disorders
 
28 Inherited and Acquired Coagulation Disorders
 
29 Thrombosis and Antithrombotic Therapy
 
30 Hematologic Aspects of Systemic Diseases
 
31 Parasitic Disorders
 
32 Blood Transfusion
 
Appendix 1 2016 World Health Organization Classification of Lymphoid and Myeloid Neoplasms
 
Index xxx

About the author

A. Victor Hoffbrand, MA, DM, FRCP, FRCPath, DSc, FMed Sci, is Emeritus Professor of Haematology at University College, London, UK. Paresh Vyas, FRCP, FRCPath, DPhil, is Professor of Haematology, Director of Oxford Centre for Haematology, Honorary Consultant Haematologist and Group Leader, MRC Molecular Haematology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. Elías Campo, MD, is Senior Consultant and Research Director, Hospital Clinic of Barcelona, and Professor of Anatomical Pathology at University of Barcelona, Faculty of Medicine, Barcelona, Spain. Torsten Haferlach, MD, MLL Munich Leukemia Laboratory, Munich, Germany. Keith Gomez, MBBS, MRCP, FRCPath, PhD, is Consultant Haematologist at Royal Free London NHS Foundation Trust, UK.

Summary

Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice

The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day.

Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems.
* Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images
* Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities
* Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format
* Includes and illustrates the WHO Classification of Hematologic Malignancies
* Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases

Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.

Product details

• Authors: Elias Campo, Elias et a Campo, Elias et al Campo, Keith Gomez, Torsten Haferlach, A Victo Hoffbrand, A Victor Hoffbrand, A. Victor Hoffbrand, A. Victor (University College Hoffbrand, A. Victor Vyas Hoffbrand, V Hoffbrand, Victor Hoffbrand, Victor (Royal Free Hospital London) Vya Hoffbrand, Victor (University College Hoffbrand, Pares Vyas, Paresh Vyas
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 31.12.2018
• EAN: 9781119057017
• ISBN: 978-1-119-05701-7
• No. of pages: 600
• Subject: Natural sciences, medicine, IT, technology > Medicine > General