In silico interaction of Bio-active compounds against Pseudomonas spp - Pseudomonas syringae,Triticum aestivum

Different strains of Pseudomonas syringae are affecting a large number of plant worldwide. But still there was a need to identified potential bioactive compound which will react with Pseudomonas syringae with showing antimicrobial activity. The compounds from different 14 plant sources, previously known to have antibacterial properties, were virtually screened to identify side effects free natural drug. Molecular docking identified Twenty potential compounds (Procyanidin B2, Nimolicinol, Rutin, Xanthophyll, Withanolide, Hyperoside, Astragalin, Nimbaflavone, Tiplasinin, Chrysophanol, Emodin, 9,11-Dehydroergosterol peroxide, Ergosterol Peroxide, Haematoxylin, Ellagic Acid, Liquiritin, Azadiradione, Meldenin, Vilasinin, Bergenin) found to have perfect binding with reported HrcQB protein of Pseudomonas syringae bacteria.The results show that Procyanidin B2 having a highest binding affinity of -7.1, second is the Nimolicinol with binding affinity of -6.9 and then Rutin and Xanthophyll with binding affinity of -6.7.The potential of Bioactive compounds against Pseudomonas syringae bacteria has best been highlighted through this studied

Product details

• Authors: Dhruvin Vadee
• Assisted by: Rishe Kalaria (Editor), Rishee Kalaria (Editor)
• Publisher: LAP Lambert Academic Publishing
• Languages: English
• Product format: Paperback / Softback
• Released: 31.07.2018
• EAN: 9786139871971
• ISBN: 9786139871971
• No. of pages: 104
• Subject: Natural sciences, medicine, IT, technology > Biology > Agriculture, horticulture; forestry, fishing, food